类风湿关节炎细胞因子与中医体质分布的相关性探究

Study on the Correlation between Cytokines of Rheumatoid Arthritis and TCM Constitution Distribution

类风湿关节炎是一种临床常见手足区域小关节呈对称、肿胀、疼痛、多关节受累的慢性、侵蚀性关节炎症为主要特征的难治性自身免疫病,致残率高。中医称为“痹病”或“尪痹”。本课题从中医体质角度出发,得出结论:本病与年龄、性别及中医体质存在联系,其中IL-1在中医阳虚质及非阳虚质的人群对比中的差异性有统计学意义。

Rheumatoid arthritis (RA) is a kind of refractory autoimmune disease characterized by symme-trical, swelling, pain, multi joint chronic and erosive arthritis of the small joints in the hand and foot region, with high disability rate. Traditional Chinese medicine is called “Bi disease” or “Ag-gravated bi”. From the perspective of TCM Constitution, this topic draws the conclusion: The dis-ease is related to age, gender and TCM Constitution, and the difference of IL-1 in the comparison of the people with and without Yang deficiency of TCM is statistically significant.