太阴病论治结直肠癌围化疗期的感悟

The Perception of the Treatment Method of the Taiyin Disease in the Peri-Chemotherapy Period of Colorectal Cancer

化疗在结直肠癌的分期治疗中具有较广泛的应用,且取得了公允的较大获益。但化疗在改善结直肠癌患者生存状况的同时,也造成了包括胃肠道反应在内的多种毒副作用,中医药的介入能有效地改善人体对化疗药物的耐受并提高化疗效果。师法经典,笔者发现《伤寒论》中的太阴病与结直肠癌患者围化疗期的病情存在病位、病性、病机上的相似,故在结直肠癌围化疗期的分期证治中,可借鉴太阴病的治则治法:温中为主,兼顾肝肾,此外还发现太阴病的时间规律对结直肠癌的时间化疗亦有启发,由此可见经典指导临床的意义及发掘经典价值的必要性。

Chemotherapy has been widely used in staging treatment of colorectal cancer, and has achieved a fair and large benefit. However, chemotherapy has not only improved the survival condition of colorectal cancer patients, but also caused a variety of toxic and side effects including gastrointestinal reactions. TCM intervention can effectively improve the human body’s tolerance to chemotherapy drugs and improve the effect of chemotherapy. According to the classic method, we found that the condition of Taiyin disease in the typhoid theory and the condition of colorectal cancer patients in the peri-chemotherapy period are similar in the disease location and pathogenesis. Therefore, in the treatment of stage syndrome in the peri-chemotherapy period of colorectal cancer, the treatment method of Taiyin disease can be used for reference: temperature-centered, giving consideration to both liver and kidney. In addition, we also found that the regularity of the time of Taiyin disease is also enlightening to the time chemotherapy of colorectal cancer. Thus, it can be seen the significance of classical guidance in clinical practice and the necessity of exploring classical value.