摘要
多囊卵巢综合症(Polycystic Ovary Syndrome, PCOS)是涉及生殖、内分泌、代谢、免疫等多系统紊乱的高度异质性疾病。著名妇产科、中西结合专家俞瑾教授是国内研究PCOS最早、视角独到,认识深刻的专家。她敏锐的思维和60多年的临床及科研实践,深刻阐明了PCOS网络失调的病理机制,并验证了中医药疗效机理。本文通过整理俞瑾教授多年来中医专方治疗PCOS临床及相关实验研究,从专方治疗角度,分析临床与基础研究,包括神经内分泌、组织代谢、免疫炎症因子、形态学等网络失调病变,深刻理解中西结合,辨病辩证分析治疗PCOS的内涵与机理,为临床治疗提供指导。
Polycystic Ovary Syndrome (PCOS) is a common, heterogeneous reproductive disease in women, involving multiple systems with a highly polymorphic clinical manifestation. Professor Yu Jin from the Obstetrics and Gynecology Hospital of Fudan University, has adopted an integrated approach to Chinese and Western medicine and is the pioneer researcher on PCOS in our country. Drawing on her 60 years of clinical and scientific research experiences, her profound medical knowledge and unique perspectives, Professor Yu has rationally elucidated the network pathological mechanism of PCOS and verified the effectiveness of Traditional Chinese Medicine (TCM). This article reviews Professor Yu’s experimental researches in PCOS from the perspective of TCM special prescriptions, and analyzes the pathological changes in neuroendocrine interactions, tissue metabolism, inflammatory and immune factors expressions, morphological alterations and other network disorders. It demonstrates how Western diagnosis and Chinese dialectical analysis can be integrated and provides guidance for the clinical treatment of PCOS.
出处
《中医学》
2021年第5期638-643,共6页
Traditional Chinese Medicine
