经典名方黄连汤的古今文献考证研究

Ancient Literature Textual Research and Modern Clinical Research of Huanglian Decoction

黄连汤出自《伤寒论》,作为国家中医药管理局颁布的百首经典名方之一,自产生起被历代广泛使用,同名方剂较多,但药物组成与功效在历代传承中出现了多个版本,故对该方的考证成了重中之重。本研究从古代文献考究和现代临床研究两方面进行整理分析,运用文献分析法寻其历史源流,认为黄连、炙甘草、干姜、桂枝、人参、清半夏、大枣为黄连汤基本组成药物,阴阳失调、寒热夹杂为其治疗的基本病机,现代研究认为本方可用于治疗消化系统炎性疾病,为本方复方制剂的研发提供理论基础。

Huanglian decoction is from the Treatise on Typhoid Fever. As one of the 100 classical formulas promulgated by the State Administration of Traditional Chinese Medicine, it has been widely used throughout the ages since its inception, and there are many formulas with the same name, but the composition and efficacy of the drug have been passed down through the ages in several versions. In this study, we analyze the ancient literature and modern clinical research to find the historical origin of this formula, and conclude that Huang Lian, Gan Cao, Gan Jiang, Gui Zhi, Ginseng, Han Xia and Da Zao are the basic components of Huanglian Tang, and that the disorder of Yin and Yang, and the mixture of cold and heat are the basic pathological mechanisms of its treatment. Modern research suggests that this formula can be used to treat inflammatory diseases of the digestive system, providing a theoretical basis for the development of compound formulations of this formula.