基于“络病理论”论治膜性肾病及虫类药的应用

Treatment of Membranous Nephropathy and Application of Insect Drugs Based on “Collateral Disease Theory”

膜性肾病是临床上常见的一种慢性肾小球疾病,中医学认为本病以肾络虚损为本,瘀、浊、湿、毒等邪实为标,本虚标实贯彻始终。而在现代医学中,肾脏的肾小球毛细血管网状结构与络脉迂曲的结构相似,络脉通过运行气血,输布津液来维护人体内环境稳定,与肾脏的功能存在一定的联系。本文基于络病理论,从“络”论治膜性肾病三个阶段的发病机制,并且通过文献资料及临床经验探讨虫类药在膜性肾病上的应用,以期拓展思路,为临床诊疗提供参考。

Membranous nephropathy (MN) is a common chronic glomerular disease in clinic. Traditional Chinese medicine (TCM) believes that the disease is based on the deficiency of the kidney collateral, and the pathogenic factors such as stasis, turbidity, dampness and toxin are the main symptoms. In modern medicine, the glomerular capillary network of the kidney is similar to the tortuous structure of the collaterals, which maintain the stability of the internal environment by running qi and blood and transfusing fluid, there is a certain relationship with the function of the kidney. Based on the theory of collateral disease, this paper discusses the pathogenesis of three stages of membranous nephropathy from the theory of “Collateral”, and discusses the application of insect drugs in membranous nephropathy through literature and clinical experience, in order to expand our thinking, to provide reference for clinical diagnosis and treatment.