近十年中医湿热证研究文献的知识图谱可视化分析

Visualization Analysis of Knowledge Map of Research Literature on Damp-Heat Syndrome of Traditional Chinese Medicine in Recent Ten Years

目的:应用知识图谱直观展示近十年中医湿热证的研究进展,分析湿热证的研究现状、研究热点及前沿动态,为该领域的研究提供思路与参考。方法:于中国知网(CNKI)检索自2013年7月1日至2023年7月1日湿热证研究相关文献,采用CiteSpace和VOSviewer软件,绘制湿热证研究的发文时间、作者、机构、关键词共现及突现图谱。结果:共纳入4072篇文献;核心研究者289名;研究机构271个;形成“数据挖掘”“炎症因子”“肝胆湿热证”“临床疗效”“动物模型”等23个关键词聚类标签;“肠道菌群”“数据挖掘”为强度最高的突现词。结论:湿热证研究内容主要涉及临床证候类型特征、诊疗,证候生物学基础及药理机制,名医经验及用药规律等,炎症因子、肠道菌群是热点机制,数据挖掘是热点研究方法。

Objective: To visually display the research progress of damp-heat syndrome in traditional Chinese medicine in recent ten years by using knowledge map, and to analyze the research status, research hotspots and frontier trends of damp-heat syndrome, so as to provide ideas and references for the research in this field. Methods: Relevant literatures on damp-heat syndrome research from July 1, 2013 to July 1, 2023 were retrieved from China National Knowledge Infrastructure (CNKI). CiteSpace and VOSviewer software were used to draw the publication time, authors, institutions, keyword co-occurrence and burst map of damp-heat syndrome research. Results: A total of 4072 articles were included;289 core researchers;271 research institutions;form 23 keyword cluster-ing labels such as “data mining”, “inflammatory factors”, “hepatobiliary damp-heat syndrome”, “clinical efficacy”, and “animal model”;“intestinal flora” and “data mining” are the most intense burst words. Conclusion: The research content of damp-heat syndrome mainly involves the charac-teristics of clinical syndrome types, diagnosis and treatment, the biological basis and pharmacolog-ical mechanism of syndromes, the experience of famous doctors and the rules of medication. In-flammatory factors and intestinal flora are the hot mechanisms, and data mining is a hot research method.