基于“肠–肾–肺轴”论治慢性肾脏病

On Treatment of Chronic Kidney Disease Based on the “Gut-Kidney-Lung Axis”

慢性肾脏病(CKD)现已成为国际性的重要公共卫生问题,因其起病隐匿,长期处于无症状阶段,且患者对疾病的知晓率较低。往往后期发展为慢性肾功能衰竭(CFR),慢性肾衰竭(CRF)是由各种慢性肾脏病(CKD)进行性进展,导致原发性肾小球滤过率降低(GFR),以及肾部组织的机能不可逆性的降低,导致与此相关的代谢出现紊乱以及临床症状组成的综合征。近年来,“肠–肾–肺轴”理论进入CKD领域,为探索治疗CKD带来了新观点、新思路、新方法。栾仲秋教授基于“肠–肾–轴”理论,受中医学“少阳属肾,肾上连肺,故将两脏”思想的启发,为临床治疗CKD治疗提供了可行性的思路与方法。

Chronic Kidney Disease (CKD) has become an important international public health problem, because of its insidious onset, long-term asymptomatic stage, and low awareness rate of patients. It often develops into Chronic Renal Failure (CFR) at a later stage. Chronic Renal Failure (CRF) is a syndrome characterized by the progressive progression of various Chronic Kidney Diseases (CKD) resulting in a decrease in primary Glomerular Filtration Rate (GFR) and an irreversible decrease in the function of renal tissues, resulting in metabolic disorders and clinical symptoms associated with it. In recent years, the theory of “gut-kidney-lung axis” has entered the field of CKD, bringing new perspectives, new ideas and new methods to explore the treatment of CKD. Based on the theory of “gut-kidney-axis”, Professor Zhongqiu Luan was inspired by the idea that “less yang belongs to the kidney, and the kidney is connected to the lungs, so the two organs are connected”, which provides feasible ideas and methods for the clinical treatment of CKD.