石菖蒲的临床应用与现代药理学研究

Clinical Applications and Modern Pharmacological Studies on Acorus tatarrinowii Schott

石菖蒲有开窍豁痰、醒神益智、化湿开胃等功效,其临床主要运用于健忘、神志昏迷、胃脘胀痛、耳鸣、耳聋、感染、抑郁焦虑等。现代药理学研究靶点为抗氧化、改善认知、改善细胞凋亡、抗癫痫、神经保护、抑制胃肠收缩、抗菌、抗肿瘤等等。对神经系统、消化系统、五官系统等疾病,药理活性显著,临床运用广泛。煎剂用量为3~30 g,在临床使用中还需要考虑到辨证论治,进行合理运用。本文通过总结石菖蒲的临床运用和药理学研究,以期为石菖蒲的临床和进一步研究提供参考。Acorus tatarrinowii Schott has the effect of opening the orifices and expelling phlegm, awakening the mind and wisdom, dissolving dampness and opening the stomach, etc. Its clinical application is mainly used in amnesia, delirium, gastric distension, tinnitus, deafness, infection, depression and anxiety. Modern pharmacological research targets for antioxidant, improve cognition, improve apoptosis, anti-epilepsy, neuroprotection, inhibit gastrointestinal contraction, antibacterial, anti-tumour and so on. It has significant pharmacological activity and wide clinical use in diseases of the nervous system, digestive system, and five sensory systems. The dosage of the decoction is 3~30 g, and it also needs to take into account the identification and treatment for rational application in clinical use. This paper summarizes the clinical use and pharmacological study of Acorus tatarrinowii Schott, with a view to providing reference for the clinical and further study of Acorus calamus.