结直肠癌靶向药物治疗的应用与进展

Application and Progress of Targeted Drug Therapy for Colorectal Cancer

在我国,结直肠癌发病率呈逐年增加趋势,靶向药物联合化疗已成为晚期结直肠癌治疗的趋势所在,近几年随着靶向药物治疗的应用,很大程度上延长了晚期结直肠癌患者的生存期。同时,由于对结直肠癌病因学、分子生物学、细胞学的不断升入研究及相关试验开展,新的靶向药物不断涌现。本文综述了结直肠癌靶向治疗的临床应用与研究进展。

In China, the incidence rate of colorectal cancer is increasing year by year. Targeted drug combination chemotherapy has become the trend of treatment for advanced colorectal cancer. In recent years, with the application of targeted drug therapy, the survival time of patients with advanced colorectal cancer has been greatly extended. At the same time, with the development of the research on the etiology, molecular biology and cytology of colorectal cancer, new targeted drugs are emerging. This paper reviews the clinical application and research progress of targeted therapy for colorectal cancer.