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Epithelial-Mesenchymal Transition and Breast Cancer Stem Cells in Breast Cancer Progression

Epithelial-Mesenchymal Transition and Breast Cancer Stem Cells in Breast Cancer Progression
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摘要 Breast cancer stem cells (BCSCs) are a small subpopulation of cancer cells having the ability of self-renewing and multi-lineage differentiation, which have also been termed as “tumor-initiating cells”. And in recent years, the role of epithelial mesenchymal transition (EMT) in malignant tumors has been valued. This paper will briefly review and discuss the relationship between BCSCs and EMT. Breast cancer stem cells (BCSCs) are a small subpopulation of cancer cells having the ability of self-renewing and multi-lineage differentiation, which have also been termed as “tumor-initiating cells”. And in recent years, the role of epithelial mesenchymal transition (EMT) in malignant tumors has been valued. This paper will briefly review and discuss the relationship between BCSCs and EMT.
作者 Wanyue Han Qingshan Li Qing Zhang Fan Xu Wanyue Han;Qingshan Li;Qing Zhang;Fan Xu(The Affiliated Hospital of Chengde Medical University, Chengde, China)
出处 《Advances in Breast Cancer Research》 2022年第2期141-151,共11页 乳腺癌(英文)
关键词 Epithelial-Mesenchymal Transition Breast Cancer Stem Cells E-CADHERIN VIMENTIN Signaling Pathway Epithelial-Mesenchymal Transition Breast Cancer Stem Cells E-Cadherin Vimentin Signaling Pathway
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