摘要
It has been known since March 2013 that Artesunate is considered the gold standard treatment for severe malaria <a href="#ref1">[1]</a> <a href="#ref2">[2]</a> <a href="#ref3">[3]</a>. However, in our regions, the drug of choice available to treat patients with severe malaria remains quinine until today. However, frequent and sequential use of quinine is associated with the occurrence of hemoglobinuria <a href="#ref2">[2]</a>. We report a probable case of bilious hemoglobin fever (BHF) in an 8-year-old child. This was an 8-year-old child with a history of frequent and recent treatment with quinine, received in consultation for coca-cola urine emission with rapid diagnostic test (RDT) positive. In search of a particular terrain, the retroviral and syphilitic serologies were negative. Considering the context, the diagnosis of post-quinine hemoglobin bilious fever (BHF) was retained and the patient had progressed well after administration of artemisinin and its derivatives. The child was followed, on an outpatient basis, without any sequelae. It would therefore be prudent for the time being to avoid them in prophylaxis and self-medication.
It has been known since March 2013 that Artesunate is considered the gold standard treatment for severe malaria <a href="#ref1">[1]</a> <a href="#ref2">[2]</a> <a href="#ref3">[3]</a>. However, in our regions, the drug of choice available to treat patients with severe malaria remains quinine until today. However, frequent and sequential use of quinine is associated with the occurrence of hemoglobinuria <a href="#ref2">[2]</a>. We report a probable case of bilious hemoglobin fever (BHF) in an 8-year-old child. This was an 8-year-old child with a history of frequent and recent treatment with quinine, received in consultation for coca-cola urine emission with rapid diagnostic test (RDT) positive. In search of a particular terrain, the retroviral and syphilitic serologies were negative. Considering the context, the diagnosis of post-quinine hemoglobin bilious fever (BHF) was retained and the patient had progressed well after administration of artemisinin and its derivatives. The child was followed, on an outpatient basis, without any sequelae. It would therefore be prudent for the time being to avoid them in prophylaxis and self-medication.
作者
Dieudonné Lobela Bumba
Issa Yakusu Issa
Bruce Wembolua Shinga
Muyobela Kampunzu
Gilbert Bokungu Isongibi
Francy Baelongandi Folo
Jacques Ossinga Bassandja
Dieudonné Lobela Bumba;Issa Yakusu Issa;Bruce Wembolua Shinga;Muyobela Kampunzu;Gilbert Bokungu Isongibi;Francy Baelongandi Folo;Jacques Ossinga Bassandja(Higher Institute of Medical Techniques of Yangambi, Yangambi, Democratic Republic of Congo;Yalosase Health Center, Rural Health Zone of Isangi, Isangi, Democratic Republic of Congo;Lomboto Reference Health Center, Isangi Rural Health Zone, Isangi, Democratic Republic of Congo;Department of Internal Medicine, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of Congo;Infectious and Tropical Diseases Department, National University Hospital of Fann, Dakar, Senegal;Department of Pediatrics, Faculty of Medicine and Pharmacy, University of Kisangani, Kisangani, Democratic Republic of Congo;Provincial Health Division, Tshopo, Democratic Republic of Congo)
