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Lack of Association between Impulse Control Disorders and REM Sleep Behavior Disorder in Patients with Parkinson’s Disease

Lack of Association between Impulse Control Disorders and REM Sleep Behavior Disorder in Patients with Parkinson’s Disease
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摘要 Purpose: Rapid eye movement sleep behavior disorder (RBD) and impulse control disorders (ICDs) are common in subjects with Parkinson’s disease. The association between these two conditions has been contradictory. The aim of this study is to analyze the association between these two non-motor symptoms. Methods: Consecutive subjects with Parkinson’s disease attending the Movement Disorders Outpatient Clinic were included. The presence of ICDs was assessed using the Questionnaire for Impulse Control Disorders Rating Scale. RBD was diagnosed by an overnight, single night polysomnography. Results: Fifty-five consecutive subjects with Parkinson’s disease were included. The prevalence of ICDs and related behaviors was 23.6% (ICD in 14.5% and related behaviors in 9.1%). RBD was diagnosed in 47.2% of the patients. No differences were found in the frequency of ICDs and related behaviors when comparing subjects with and without RBD (23% versus 24.1%, p = 0.926, respectively). Conclusion: No association between the presence of RBD and the frequency of ICDs in subjects with Parkinson’s disease was found. Purpose: Rapid eye movement sleep behavior disorder (RBD) and impulse control disorders (ICDs) are common in subjects with Parkinson’s disease. The association between these two conditions has been contradictory. The aim of this study is to analyze the association between these two non-motor symptoms. Methods: Consecutive subjects with Parkinson’s disease attending the Movement Disorders Outpatient Clinic were included. The presence of ICDs was assessed using the Questionnaire for Impulse Control Disorders Rating Scale. RBD was diagnosed by an overnight, single night polysomnography. Results: Fifty-five consecutive subjects with Parkinson’s disease were included. The prevalence of ICDs and related behaviors was 23.6% (ICD in 14.5% and related behaviors in 9.1%). RBD was diagnosed in 47.2% of the patients. No differences were found in the frequency of ICDs and related behaviors when comparing subjects with and without RBD (23% versus 24.1%, p = 0.926, respectively). Conclusion: No association between the presence of RBD and the frequency of ICDs in subjects with Parkinson’s disease was found.
作者 Lisette Bazán-Rodríguez Mayela Rodríguez-Violante Amin Cervantes-Arriaga Guillermo Parra-López Diego Cruz-Fino Francisco Pascasio-Astudillo Vanessa Alatriste-Booth Lisette Bazán-Rodríguez;Mayela Rodríguez-Violante;Amin Cervantes-Arriaga;Guillermo Parra-López;Diego Cruz-Fino;Francisco Pascasio-Astudillo;Vanessa Alatriste-Booth(Clinical Laboratory of Neurodegenerative Diseases, National Institute of Neurology and Neurosurgery, Mexico City, Mexico;Movement Disorders Clinic, National Institute of Neurology and Neurosurgery, Mexico City, Mexico;Sleep Disorders Unit, National Institute of Neurology and Neurosurgery, Mexico City, Mexico)
出处 《Advances in Parkinson's Disease》 2016年第4期67-72,共7页 帕金森(英文)
关键词 Parkinson’s Disease Impulse Control Disorders REM Sleep Behavior Disorder Parkinson’s Disease Impulse Control Disorders REM Sleep Behavior Disorder
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