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Osteonecrosis: The perils of steroids. A review of the literature and case report

Osteonecrosis: The perils of steroids. A review of the literature and case report
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摘要 Non-traumatic osteonecrosis is a cause of joint pain and deformity, not uncommonly caused by corticosteroid use. Despite this, corticosteroid induced osteonecrosis is poorly represented in the literature. We performed a detailed review of corticosteroid induced osteonecrosis, including aetiology, prevention, screening, clinical presentation, investigations, staging systems and treatment. We present this in the context of a patient at our institution who developed bilateral hip, shoulder and knee osteonecrosis following high dose corticosteroid therapy for dermatomyositis. Non-traumatic osteonecrosis is a cause of joint pain and deformity, not uncommonly caused by corticosteroid use. Despite this, corticosteroid induced osteonecrosis is poorly represented in the literature. We performed a detailed review of corticosteroid induced osteonecrosis, including aetiology, prevention, screening, clinical presentation, investigations, staging systems and treatment. We present this in the context of a patient at our institution who developed bilateral hip, shoulder and knee osteonecrosis following high dose corticosteroid therapy for dermatomyositis.
出处 《Case Reports in Clinical Medicine》 2012年第2期26-37,共12页 临床医学病理报告(英文)
关键词 OSTEONECROSIS CORTICOSTEROIDS STEROIDS AVASCULAR NECROSIS of Bone Osteonecrosis Corticosteroids Steroids Avascular Necrosis of Bone
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