摘要
We report here a 17-year-old boy with a complicated presentation of undifferentiated juvenile idiopathic arthritis, vision-threatening uveitis and chronic recurrent multifocal osteomyelitis (CRMO) in the pelvis. His severe iritis needed subtenon injections and only responded to infliximab after failing multiple biologics. Unfortunately he later developed infliximab-associated psoriasis. A combination of infliximab and ustekinumab induced remission of his arthritis, osteomyelitis, uveitis and psoriasis without experiencing severe infections.
We report here a 17-year-old boy with a complicated presentation of undifferentiated juvenile idiopathic arthritis, vision-threatening uveitis and chronic recurrent multifocal osteomyelitis (CRMO) in the pelvis. His severe iritis needed subtenon injections and only responded to infliximab after failing multiple biologics. Unfortunately he later developed infliximab-associated psoriasis. A combination of infliximab and ustekinumab induced remission of his arthritis, osteomyelitis, uveitis and psoriasis without experiencing severe infections.
作者
Yongdong Zhao
Shannon K. Foster
Todd J. Murdock
Margret Schlesinger
Carol A. Wallace
Yongdong Zhao;Shannon K. Foster;Todd J. Murdock;Margret Schlesinger;Carol A. Wallace(Pediatric Rheumatology, Seattle Children’s Hospital, Seattle, WA, USA;Western Montana Clinic, Missoula, MT, USA;Rocky Mountain Eye Center, Missoula, MT, USA)
