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Rheumatic Mineralization of Aortic Valve and Anterior Mitral Leaflet—A Case Report

Rheumatic Mineralization of Aortic Valve and Anterior Mitral Leaflet—A Case Report
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摘要 Aim: To present the heterotopic ossification of left-sided heart valves due to rheumatic inflammation and biomineralization. Introduction: Calcification in the region of mitral-aortic continuity is significant at its origin and etiopathogenesis. The etiology of valvular calcification may be divided into 3 groups, namely, inflammation, degeneration and metabolic disturbances. Calcification of cardiac valve leaflets is most often due to rheumatic etiology in tropical nations. Case Report: A 52-year-old male developed sudden onset of light-headedness and palpitations due to atrial fibrillation. Transthoracic 2D echocardiography revealed calcification of anterior mitral leaflet and aortic valve which resembles a bone-like structure and the patient was advised double valve replacement. Conclusion: It was known that the cellular mechanisms play an important role in its genesis and therapeutic strategies are targeted to reverse this process by understanding its biological mediators. Aim: To present the heterotopic ossification of left-sided heart valves due to rheumatic inflammation and biomineralization. Introduction: Calcification in the region of mitral-aortic continuity is significant at its origin and etiopathogenesis. The etiology of valvular calcification may be divided into 3 groups, namely, inflammation, degeneration and metabolic disturbances. Calcification of cardiac valve leaflets is most often due to rheumatic etiology in tropical nations. Case Report: A 52-year-old male developed sudden onset of light-headedness and palpitations due to atrial fibrillation. Transthoracic 2D echocardiography revealed calcification of anterior mitral leaflet and aortic valve which resembles a bone-like structure and the patient was advised double valve replacement. Conclusion: It was known that the cellular mechanisms play an important role in its genesis and therapeutic strategies are targeted to reverse this process by understanding its biological mediators.
出处 《Case Reports in Clinical Medicine》 2017年第4期95-119,共25页 临床医学病理报告(英文)
关键词 RHEUMATIC MINERALIZATION Mitral-Aortic “J-Shaped” Calcification “Mushroom Shaped” Calcified Bicuspid AORTIC Valve Hutchinson-Gilford PROGERIA Syndrome Therapeutic Strategies Rheumatic Mineralization Mitral-Aortic “J-Shaped” Calcification “Mushroom Shaped” Calcified Bicuspid Aortic Valve Hutchinson-Gilford Progeria Syndrome Therapeutic Strategies
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