摘要
To date, the coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic and public health disaster. In addition to acute respiratory manifestations, patients with COVID-19 exhibit other non-respiratory manifestations, particularly in those with severe underlying disease. Few specific therapeutics are effective for COVID-19, and supportive care is the primary remedy. Here, we comprehensively surveyed the most recent reports on extrapulmonary complications of COVID-19 and their corresponding treatments, as well as the comparison of different clinical symptoms and complications of COVID-19, severe acute respiratory syndrome (SARS), and the Middle East respiratory syndrome (MERS) patients. We wish to provide a molecular and cellular understanding of the complications of COVID-19 and provide guidance for future diagnostics, therapeutics, and prognostics of COVID-19.
To date, the coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic and public health disaster. In addition to acute respiratory manifestations, patients with COVID-19 exhibit other non-respiratory manifestations, particularly in those with severe underlying disease. Few specific therapeutics are effective for COVID-19, and supportive care is the primary remedy. Here, we comprehensively surveyed the most recent reports on extrapulmonary complications of COVID-19 and their corresponding treatments, as well as the comparison of different clinical symptoms and complications of COVID-19, severe acute respiratory syndrome (SARS), and the Middle East respiratory syndrome (MERS) patients. We wish to provide a molecular and cellular understanding of the complications of COVID-19 and provide guidance for future diagnostics, therapeutics, and prognostics of COVID-19.
作者
Linling Li
Ruitao Zhang
Fang Li
Chufan Xiao
Bowen Zhong
Shiyao Zhai
Changyue Liu
Qiuyue Hu
Juan Lyu
Ming Yang
Chengming Yang
Li Lyu
Yan Li
Dongmei Yu
Linling Li;Ruitao Zhang;Fang Li;Chufan Xiao;Bowen Zhong;Shiyao Zhai;Changyue Liu;Qiuyue Hu;Juan Lyu;Ming Yang;Chengming Yang;Li Lyu;Yan Li;Dongmei Yu(Shenzhen Maternity and Child Healthcare Hospital, Affiliated to Southern Medical University, Shenzhen, China;School of Mechanical, Electrical & Information Engineering, Shandong University, Weihai, China;Center of Precision Medicine and Healthcare, Tsinghua-Berkeley Shenzhen Institute, Shenzhen, China;Southern University of Science and Technology Hospital, Shenzhen, China;Shenzhen People’s Hospital, Affiliated to Southern Medical University, Shenzhen, China)
