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Study on the Safety of Different Pressure Artificial Pneumothorax on Endoscopic Radical Esophagectomy

Study on the Safety of Different Pressure Artificial Pneumothorax on Endoscopic Radical Esophagectomy
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摘要 Objective: To study the effect of different pressure artificial pneumothorax on total endoscopic radical esophagectomy during and after an operation. Methods: From 2019 to 2021, 64 patients with esophageal cancer underwent video-assisted thoracoscopic surgery in the same surgical treatment group. The pressure of CO<sub>2</sub> artificial pneumothorax was randomly divided into Group A (pressure 6 mmHg), Group B (pressure 8 mmHg), and Group C (pressure 10 mmHg). Heart rate (HR), mean arterial pressure (MAP), end-expiratory CO<sub>2</sub> partial pressure (PETCO<sub>2</sub>), arterial blood pH and PaCO<sub>2</sub>, operation time, intraoperative blood loss, and anesthesia resuscitation time were recorded at different time points. Observe the changes in inflammatory indexes, coagulation function, and the incidence of complications in the three groups, and statistically analyze and compare the differences among the three groups of patients. Results: Sixty-four patients with esophageal cancer were included in this clinical study. There were no significant differences in gender, age, lung function, BMI, and coagulation function among the three groups (P > 0.05). There were significant differences in PETCO<sub>2</sub>, arterial pH, and PaCO<sub>2</sub> in T2, T3, and T4 among the three groups (P < 0.05). The arterial blood gas index at T5 in Group A was significantly different from that in Group C (P < 0.05). The time of thoracic operation in Group A was significantly longer than that in the other two groups (P < 0.05), and the time of tracheal intubation and extubation was earlier in Group A (P < 0.05). The incidence of subcutaneous emphysema, thoracic tube time, and prothrombin time in Group A was significantly different from those in Group B and C (P < 0.05). There were no significant differences in hospitalization days, pulmonary infection, and other complications (P > 0.05). Conclusion: The artificial pneumothorax with 6 mmHg pressure and 8 L/min flow rate can satisfy the operation, and its safety and postoperative recovery are also better. Objective: To study the effect of different pressure artificial pneumothorax on total endoscopic radical esophagectomy during and after an operation. Methods: From 2019 to 2021, 64 patients with esophageal cancer underwent video-assisted thoracoscopic surgery in the same surgical treatment group. The pressure of CO<sub>2</sub> artificial pneumothorax was randomly divided into Group A (pressure 6 mmHg), Group B (pressure 8 mmHg), and Group C (pressure 10 mmHg). Heart rate (HR), mean arterial pressure (MAP), end-expiratory CO<sub>2</sub> partial pressure (PETCO<sub>2</sub>), arterial blood pH and PaCO<sub>2</sub>, operation time, intraoperative blood loss, and anesthesia resuscitation time were recorded at different time points. Observe the changes in inflammatory indexes, coagulation function, and the incidence of complications in the three groups, and statistically analyze and compare the differences among the three groups of patients. Results: Sixty-four patients with esophageal cancer were included in this clinical study. There were no significant differences in gender, age, lung function, BMI, and coagulation function among the three groups (P > 0.05). There were significant differences in PETCO<sub>2</sub>, arterial pH, and PaCO<sub>2</sub> in T2, T3, and T4 among the three groups (P < 0.05). The arterial blood gas index at T5 in Group A was significantly different from that in Group C (P < 0.05). The time of thoracic operation in Group A was significantly longer than that in the other two groups (P < 0.05), and the time of tracheal intubation and extubation was earlier in Group A (P < 0.05). The incidence of subcutaneous emphysema, thoracic tube time, and prothrombin time in Group A was significantly different from those in Group B and C (P < 0.05). There were no significant differences in hospitalization days, pulmonary infection, and other complications (P > 0.05). Conclusion: The artificial pneumothorax with 6 mmHg pressure and 8 L/min flow rate can satisfy the operation, and its safety and postoperative recovery are also better.
作者 Yafei Bao Lei Zhang Liang Zhen Bo Jiang Chen Yang Yafei Bao;Lei Zhang;Liang Zhen;Bo Jiang;Chen Yang(Department of Thoracic Surgery, Affiliated Hospital of Yangzhou University, Yangzhou, China;Department of Thoracic Surgery, The First People’s Hospital of Changzhou, Changzhou, China)
出处 《Journal of Cancer Therapy》 2022年第4期206-217,共12页 癌症治疗(英文)
关键词 Esophageal Cancer Minimally Invasive Surgery Single Lumen Tracheal Intubation Artificial Pneumothorax Esophageal Cancer Minimally Invasive Surgery Single Lumen Tracheal Intubation Artificial Pneumothorax
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