摘要
Male pattern baldness or androgenic alopecia is a great problem for many individuals’ especially young people. A100 is composed of two active ingredients, a pollen extract and pentane-1,5-diol. The pollen extract provides a source of natural nutrients and pentane-1,5-diol acts as a solvent to unplug the hair follicle as well as acts as an enhancer for uptake of nutrients. Other components are claimed to increase blood flow to the hair papilla. A100 has been effective in earlier studies. The aim of this open explanatory study was to investigate the effect of 4 months twice daily application with this commercial pollen gel, A100, in subjects with male androgenic alopecia. Twenty male subjects, between 18 and 40 years with androgenic alopecia were included. A100 gel was applied to the area of the scalp with poor hair growth twice daily for 4 months. The subjects were seen at the start of treatment and then every month. Sixteen subjects fulfilled the whole 4 months of treatment and 2 fulfilled 3 months of treatment. A statistically significant increase in number of hairs was seen after 4 months of treatment with A100 (p < 0.001). This effect was seen for all types of hair. Fifty-six percent of the 16 subjects who fulfilled the 4 months treatment had an increase in hair growth of more than 50%, and 31% had an increase over 100%. No side effects were seen and the subjects found A100 gel a cosmetically attractive treatment. A100 was in this explanatory study an effective and safe treatment for androgenic alopecia or male pattern baldness.
Male pattern baldness or androgenic alopecia is a great problem for many individuals’ especially young people. A100 is composed of two active ingredients, a pollen extract and pentane-1,5-diol. The pollen extract provides a source of natural nutrients and pentane-1,5-diol acts as a solvent to unplug the hair follicle as well as acts as an enhancer for uptake of nutrients. Other components are claimed to increase blood flow to the hair papilla. A100 has been effective in earlier studies. The aim of this open explanatory study was to investigate the effect of 4 months twice daily application with this commercial pollen gel, A100, in subjects with male androgenic alopecia. Twenty male subjects, between 18 and 40 years with androgenic alopecia were included. A100 gel was applied to the area of the scalp with poor hair growth twice daily for 4 months. The subjects were seen at the start of treatment and then every month. Sixteen subjects fulfilled the whole 4 months of treatment and 2 fulfilled 3 months of treatment. A statistically significant increase in number of hairs was seen after 4 months of treatment with A100 (p < 0.001). This effect was seen for all types of hair. Fifty-six percent of the 16 subjects who fulfilled the 4 months treatment had an increase in hair growth of more than 50%, and 31% had an increase over 100%. No side effects were seen and the subjects found A100 gel a cosmetically attractive treatment. A100 was in this explanatory study an effective and safe treatment for androgenic alopecia or male pattern baldness.
作者
Jan Faergemann
Thomas Hedner
Jan Faergemann;Thomas Hedner(Department of Dermatology, Sahlgrenska University Hospital, Gothenburg, Sweden;Department of Clinical Pharmacology, Sahlgrenska University Hospital, Gothenburg, Sweden)
