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Viral Hepatitis C during a Screening Campaign in General Population of Benin: Seroprevalence and Associated Factors

Viral Hepatitis C during a Screening Campaign in General Population of Benin: Seroprevalence and Associated Factors
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摘要 <span style="font-family:Verdana;"><strong>Introduction:</strong> Hepatitis C is a global public health problem. The purpose of this study was to determine the prevalence and factors associated with hepatitis C virus (HCV) antibody carriage during mass screening in several localities throughout Benin. <strong>Methods:</strong> This was a descriptive and analytical cross-sectional study with prospective data collection. This collection took place from 20 to 28 July 2019 at a free voluntary hepatitis C screening organized in Benin by Rotary Clubs in 23 sites throughout the country. A rapid diagnostic orientation test was used for the detection of anti-HCV antibodies. <strong>Results: </strong>A total of 9035 voluntary participants were included, mostly of Beninese nationality (99.0%), with a median age of 27 years, of whom 51.1% (4619/9035) were single and mainly schoolchildren, pupils or students (37.9%;3426/9035). HCV seroprevalence was 1.0% (87/9035) [95% CI = 0.8% - 1.2%]. This infection was associated with age greater than 42 years (ORa = 2.71;95% CI: 1.06 - 6.95), p < 0.03, and history of diabetes (ORa = 3.9;95% CI: 1.9 - 7.6). <strong>Conclusion:</strong> HCV antibody seroprevalence is relatively low in the study population: 1%. Factors associated with HCV antibody carriage were age, occupation and diabetic history.</span> <span style="font-family:Verdana;"><strong>Introduction:</strong> Hepatitis C is a global public health problem. The purpose of this study was to determine the prevalence and factors associated with hepatitis C virus (HCV) antibody carriage during mass screening in several localities throughout Benin. <strong>Methods:</strong> This was a descriptive and analytical cross-sectional study with prospective data collection. This collection took place from 20 to 28 July 2019 at a free voluntary hepatitis C screening organized in Benin by Rotary Clubs in 23 sites throughout the country. A rapid diagnostic orientation test was used for the detection of anti-HCV antibodies. <strong>Results: </strong>A total of 9035 voluntary participants were included, mostly of Beninese nationality (99.0%), with a median age of 27 years, of whom 51.1% (4619/9035) were single and mainly schoolchildren, pupils or students (37.9%;3426/9035). HCV seroprevalence was 1.0% (87/9035) [95% CI = 0.8% - 1.2%]. This infection was associated with age greater than 42 years (ORa = 2.71;95% CI: 1.06 - 6.95), p < 0.03, and history of diabetes (ORa = 3.9;95% CI: 1.9 - 7.6). <strong>Conclusion:</strong> HCV antibody seroprevalence is relatively low in the study population: 1%. Factors associated with HCV antibody carriage were age, occupation and diabetic history.</span>
作者 Moussiliou Noel Paraiso Aboudou Raïmi Kpossou Comlan N’dehougbèa Sokpon Hervé Lawin Cédric Bigot Rodolph Koffi Vignon René Keke Moussiliou Noel Paraiso;Aboudou Raïmi Kpossou;Comlan N’dehougbèa Sokpon;Hervé Lawin;Cédric Bigot;Rodolph Koffi Vignon;René Keke(Regional Institute of Public Health, Ouidah, Benin;Faculty of Health Sciences, University of Abomey-Calavi, Abomey-Calavi, Benin;National and University Hsopital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin)
出处 《Open Journal of Epidemiology》 2021年第2期178-188,共11页 流行病学期刊(英文)
关键词 Hepatitis C Virus Epidemiological Profile BENIN Hepatitis C Virus Epidemiological Profile Benin
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