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What Impact Does COVID-19 Have in Cirrhotics?

What Impact Does COVID-19 Have in Cirrhotics?
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摘要 SARS-Cov-2 is a novel coronavirus discovered in Wuhan, China in late 2019 and responsible for respiratory distress. <strong><u>Aim:</u></strong> study the impact of COVID-19 among patients with cirrhosis. <strong><u>Patients and methods:</u></strong> We conducted a prospective study for a period of 9 months (April 1st-December 1st) that included cirrhotic patients infected with SARS-Cov-2 followed in the gastroenterology department in the University Hospital Hassan II. <strong><u>Results:</u></strong> Among 1437 patients hospitalised for SARS-Cov-2, 8 cirrhotic patients were included in a period of 9 months (April 1st-December 1st). The mean age is 55 y/o and most are female (n = 6). The aetiology of cirrhosis is mostly HCV (n = 3), HBV (n = 2). Half of the infected patients had acute bleeding (one of them had hepatic encephalopathy) and one patient had respiratory distress. Most of the patients had a negative PCR at the end of the hospital stay (n = 5). The mortality rate was 25% and patients were followed up for a period of 4 months. <strong><u>Conclusion:</u></strong> In the studied population, clinical manifestations were essentially a decompensation of cirrhosis. SARS-Cov-2 is a novel coronavirus discovered in Wuhan, China in late 2019 and responsible for respiratory distress. <strong><u>Aim:</u></strong> study the impact of COVID-19 among patients with cirrhosis. <strong><u>Patients and methods:</u></strong> We conducted a prospective study for a period of 9 months (April 1st-December 1st) that included cirrhotic patients infected with SARS-Cov-2 followed in the gastroenterology department in the University Hospital Hassan II. <strong><u>Results:</u></strong> Among 1437 patients hospitalised for SARS-Cov-2, 8 cirrhotic patients were included in a period of 9 months (April 1st-December 1st). The mean age is 55 y/o and most are female (n = 6). The aetiology of cirrhosis is mostly HCV (n = 3), HBV (n = 2). Half of the infected patients had acute bleeding (one of them had hepatic encephalopathy) and one patient had respiratory distress. Most of the patients had a negative PCR at the end of the hospital stay (n = 5). The mortality rate was 25% and patients were followed up for a period of 4 months. <strong><u>Conclusion:</u></strong> In the studied population, clinical manifestations were essentially a decompensation of cirrhosis.
作者 Hakima Abid Hajar Cherkaoui Maria Lahlali Nada Lahmidani Mohammed El Abkari Sidi Adil Ibrahimi Hakima Abid;Hajar Cherkaoui;Maria Lahlali;Nada Lahmidani;Mohammed El Abkari;Sidi Adil Ibrahimi(Department of Hepato-gastroenterology, Hassan II University Hospital, Fez, Morocco;Faculty of Medicine and Pharmacy of Fez, University of Sidi Mohammed Ben Abdellah, Fez, Morocco)
出处 《Open Journal of Gastroenterology》 2021年第1期16-27,共12页 肠胃病学期刊(英文)
关键词 SARS-Cov-2 CIRRHOSIS DECOMPENSATION SEVERITY SARS-Cov-2 Cirrhosis Decompensation Severity
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