摘要
The corona virus disease 2019 (COVID-19) pandemic has spread globally and pregnant women are considerably prone to COVID-19 infection with increased maternal and perinatal complications. <b><span><span style="font-family:Verdana;">Aim:</span><i> </i></span></b><span style="font-family:Verdana;">This study aims to explore the risk factors that contribute to susceptibility and severity of COVID-19 infection among pregnant women. </span><b><span style="font-family:Verdana;">Method</span><span style="font-family:Verdana;">: </span></b><span style="font-family:Verdana;">A literature search of articles relating to COVID-19 infection during pregnancy, was conducted, using PubMed, Scopus and Google scholar engine. </span><b><span style="font-family:Verdana;">Result: </span></b><span style="font-family:Verdana;">A total of 168 articles were initially identified. Eighty four papers were excluded for failing to address the aim of the study. After screening titles and abstracts, eighty four full-text articles were retrieved for eligibility analysis. Nineteen studies addressed the susceptibility related to pregnancy, twenty-two studies evaluated the associated comorbidities, nineteen focused on immune system, thirty-six articles concentrated on the risk of coagulopathy and eleven addressed more than one risk factor. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">Pregnancy, associated comorbidities, modulated immune response during pregnancy and risk of coagulopathy are considerable risk factors contributing to COVID-19 pathogenesis among pregnant women and may predict the outcome.</span>
The corona virus disease 2019 (COVID-19) pandemic has spread globally and pregnant women are considerably prone to COVID-19 infection with increased maternal and perinatal complications. <b><span><span style="font-family:Verdana;">Aim:</span><i> </i></span></b><span style="font-family:Verdana;">This study aims to explore the risk factors that contribute to susceptibility and severity of COVID-19 infection among pregnant women. </span><b><span style="font-family:Verdana;">Method</span><span style="font-family:Verdana;">: </span></b><span style="font-family:Verdana;">A literature search of articles relating to COVID-19 infection during pregnancy, was conducted, using PubMed, Scopus and Google scholar engine. </span><b><span style="font-family:Verdana;">Result: </span></b><span style="font-family:Verdana;">A total of 168 articles were initially identified. Eighty four papers were excluded for failing to address the aim of the study. After screening titles and abstracts, eighty four full-text articles were retrieved for eligibility analysis. Nineteen studies addressed the susceptibility related to pregnancy, twenty-two studies evaluated the associated comorbidities, nineteen focused on immune system, thirty-six articles concentrated on the risk of coagulopathy and eleven addressed more than one risk factor. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">Pregnancy, associated comorbidities, modulated immune response during pregnancy and risk of coagulopathy are considerable risk factors contributing to COVID-19 pathogenesis among pregnant women and may predict the outcome.</span>
作者
Imad R. Musa
Imad R. Musa(Royal Commission Hospital, Jubail Industrial City, KSA)
