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Neonatal Outcome of Induced Prematurity for Severe Preeclampsia in Four Great Kinshasa Maternities

Neonatal Outcome of Induced Prematurity for Severe Preeclampsia in Four Great Kinshasa Maternities
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摘要 Severe preeclampsia (SPE) is associated with fetal complications including intrauterine growth retardation (IUGR), prematurity and in utero fetal death. Its treatment remains child birth that often is planned before term. However, this attitude can lead to fetal complications related to prematurity. Several studies on preeclampsia have already been studied in the DRC and several aspects have already been realized, but to date, the neonatal outcome has not yet been addressed. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> This is cross-sectional study performed in four public hospitals in Kinshasa (Democratic Republic of Congo). We included 400 cases of induced prematurity (IP) for SPE;the analysis compared pregnant women who gave birth before 34 weeks of amenorrhea (WA) and those after 34 WA. The comparison of the proportions was made by the Chi</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">-</span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">square test and the calculation of Means by the Student’s test. The significance level was set at P < 0.05. </span><b><span style="font-family:Verdana;">Objective:</span></b><span style="font-family:Verdana;"> To determine the frequency of induced prematurity for severe preeclampsia (SPE), to identify the indications and to evaluate neonatal outcome. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> The IP frequency for SPE was 46.2%. The retro placental hematoma was the most indication in pregnancies before 34 WA 24.9%, while high blood pressure 54.5% in the after 34 WA group. </span><i><span style="font-family:Verdana;">In</span></i> <i><span style="font-family:Verdana;">utero</span></i><span style="font-family:Verdana;"> death was more common in pregnant women who gave birth before 34 weeks 25.4%;chronic fetal distress was elevated in the after 34 WA group 19.5%. Neonatal infection was more common in the group after 34 WA </span><span style="font-family:Verdana;">49.4%, while respiratory distress 39.6%, intra and periventricular hemorrhage 19.5% and neonatal death 39.6% were more in group before 34</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">WA. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Prematurity induced for SPE is related to a poor neonatal</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> prognosis. Severe preeclampsia (SPE) is associated with fetal complications including intrauterine growth retardation (IUGR), prematurity and in utero fetal death. Its treatment remains child birth that often is planned before term. However, this attitude can lead to fetal complications related to prematurity. Several studies on preeclampsia have already been studied in the DRC and several aspects have already been realized, but to date, the neonatal outcome has not yet been addressed. </span><b><span style="font-family:Verdana;">Methods:</span></b><span style="font-family:Verdana;"> This is cross-sectional study performed in four public hospitals in Kinshasa (Democratic Republic of Congo). We included 400 cases of induced prematurity (IP) for SPE;the analysis compared pregnant women who gave birth before 34 weeks of amenorrhea (WA) and those after 34 WA. The comparison of the proportions was made by the Chi</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">-</span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">square test and the calculation of Means by the Student’s test. The significance level was set at P < 0.05. </span><b><span style="font-family:Verdana;">Objective:</span></b><span style="font-family:Verdana;"> To determine the frequency of induced prematurity for severe preeclampsia (SPE), to identify the indications and to evaluate neonatal outcome. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> The IP frequency for SPE was 46.2%. The retro placental hematoma was the most indication in pregnancies before 34 WA 24.9%, while high blood pressure 54.5% in the after 34 WA group. </span><i><span style="font-family:Verdana;">In</span></i> <i><span style="font-family:Verdana;">utero</span></i><span style="font-family:Verdana;"> death was more common in pregnant women who gave birth before 34 weeks 25.4%;chronic fetal distress was elevated in the after 34 WA group 19.5%. Neonatal infection was more common in the group after 34 WA </span><span style="font-family:Verdana;">49.4%, while respiratory distress 39.6%, intra and periventricular hemorrhage 19.5% and neonatal death 39.6% were more in group before 34</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">WA. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Prematurity induced for SPE is related to a poor neonatal</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> prognosis.
作者 Olive Yalala Ambambula Andy Muela Mbangama Therese Biselele Rashid Rahma Tozin Dieudonné Mushengezi Sengeyi Olive Yalala Ambambula;Andy Muela Mbangama;Therese Biselele;Rashid Rahma Tozin;Dieudonné Mushengezi Sengeyi(Department of Obstetrics and Gynecology, University Clinics of Kinshasa, Kinshasa, DR Congo;Department of Pediatrics, University Clinics of Kinshasa, Kinshasa, DR Congo)
出处 《Open Journal of Obstetrics and Gynecology》 2020年第11期1637-1643,共7页 妇产科期刊(英文)
关键词 PREECLAMPSIA Induced Prematurity Neonatal Outcome Preeclampsia Induced Prematurity Neonatal Outcome
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