摘要
<strong>Introduction:</strong><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> Pain control during Manual Vacuum Aspiration is one of the most important </span><span style="font-family:Verdana;">aspects</span><span style="font-family:Verdana;"> of postabortion care. This study assessed the analgesic efficacy, requirement for additional analgesia, and overall satisfaction using Paracervical blocks of 1% lignocaine compare with normal saline as </span><span style="font-family:Verdana;">placebo</span><span style="font-family:Verdana;"> among women undergoing manual vacuum aspiration for incomplete abortion in OAUTHC, Ile-Ife. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">This was a </span><span style="font-family:Verdana;">double blind</span><span style="font-family:Verdana;"> randomized controlled trial that occurred between January 2019 and February 2020. We randomized one hundred and twenty eligible women equally into 2 groups. Group A received paracervical block using 1% lignocaine while those in group B received paracervical block using normal saline as </span><span style="font-family:Verdana;">placebo</span><span style="font-family:Verdana;">. We obtained ethical cle</span><span><span style="font-family:Verdana;">arance from the Ethics and Research Committee of the hospital. Preoperatively, we obtained relevant data and evaluated the degree of anxiety and pain on a visual analog scale (VAS). Intraoperative pain was evaluated from 2 viewpoints: that of the external observer on a 0 - 4 scale and that of the patient scale of 0 - 10 in the immediate postoperative period, followed by overall satisfaction at the point of discharge. We analyzed the data using SPSS version 20. Paired </span><span style="font-family:Verdana;">T test</span><span style="font-family:Verdana;">, independent </span><span style="font-family:Verdana;">T test</span> <span style="font-family:Verdana;">Chi square</span><span style="font-family:Verdana;">, and Fishers’ exact tests were applied for continuous and categorical variables as appropriate. </span><span style="font-family:Verdana;">P value</span><span style="font-family:Verdana;"> < 0.05 was considered </span><span style="font-family:Verdana;">as</span><span style="font-family:Verdana;"> statistically significant. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> The Intra-operative and Postoperative VAS </span><span style="font-family:Verdana;">was</span><span style="font-family:Verdana;"> significantly higher in the placebo group compared to the analgesia group (t = -</span></span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">3.39, CI -</span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">4.11 - -</span><span style="font-family:Verdana;">2.69. P < 0.05 intra-operative, t = 7.18, CI 2.62 - 4.61. P < 0.05 post-operative). The need for additional analgesia and mean V</span></span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">AS of those in the placebo group was significantly higher than that of the study group with higher overall satisfaction rate in the study group (t = 7.18. CI 2.62 - 6.71. P < 0.0001). </span><b><span style="font-family:Verdana;">Conclusions:</span></b><span style="font-family:Verdana;"> Paracervical block with 1% lignocaine is more effective in reducing pain during manual vacuum aspiration compared to placebo. It has added advantage of a higher overall satisfaction rate and reduced need for additional analgesia.</span></span></span></span>
<strong>Introduction:</strong><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> Pain control during Manual Vacuum Aspiration is one of the most important </span><span style="font-family:Verdana;">aspects</span><span style="font-family:Verdana;"> of postabortion care. This study assessed the analgesic efficacy, requirement for additional analgesia, and overall satisfaction using Paracervical blocks of 1% lignocaine compare with normal saline as </span><span style="font-family:Verdana;">placebo</span><span style="font-family:Verdana;"> among women undergoing manual vacuum aspiration for incomplete abortion in OAUTHC, Ile-Ife. </span><b><span style="font-family:Verdana;">Methods: </span></b><span style="font-family:Verdana;">This was a </span><span style="font-family:Verdana;">double blind</span><span style="font-family:Verdana;"> randomized controlled trial that occurred between January 2019 and February 2020. We randomized one hundred and twenty eligible women equally into 2 groups. Group A received paracervical block using 1% lignocaine while those in group B received paracervical block using normal saline as </span><span style="font-family:Verdana;">placebo</span><span style="font-family:Verdana;">. We obtained ethical cle</span><span><span style="font-family:Verdana;">arance from the Ethics and Research Committee of the hospital. Preoperatively, we obtained relevant data and evaluated the degree of anxiety and pain on a visual analog scale (VAS). Intraoperative pain was evaluated from 2 viewpoints: that of the external observer on a 0 - 4 scale and that of the patient scale of 0 - 10 in the immediate postoperative period, followed by overall satisfaction at the point of discharge. We analyzed the data using SPSS version 20. Paired </span><span style="font-family:Verdana;">T test</span><span style="font-family:Verdana;">, independent </span><span style="font-family:Verdana;">T test</span> <span style="font-family:Verdana;">Chi square</span><span style="font-family:Verdana;">, and Fishers’ exact tests were applied for continuous and categorical variables as appropriate. </span><span style="font-family:Verdana;">P value</span><span style="font-family:Verdana;"> < 0.05 was considered </span><span style="font-family:Verdana;">as</span><span style="font-family:Verdana;"> statistically significant. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> The Intra-operative and Postoperative VAS </span><span style="font-family:Verdana;">was</span><span style="font-family:Verdana;"> significantly higher in the placebo group compared to the analgesia group (t = -</span></span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">3.39, CI -</span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">4.11 - -</span><span style="font-family:Verdana;">2.69. P < 0.05 intra-operative, t = 7.18, CI 2.62 - 4.61. P < 0.05 post-operative). The need for additional analgesia and mean V</span></span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">AS of those in the placebo group was significantly higher than that of the study group with higher overall satisfaction rate in the study group (t = 7.18. CI 2.62 - 6.71. P < 0.0001). </span><b><span style="font-family:Verdana;">Conclusions:</span></b><span style="font-family:Verdana;"> Paracervical block with 1% lignocaine is more effective in reducing pain during manual vacuum aspiration compared to placebo. It has added advantage of a higher overall satisfaction rate and reduced need for additional analgesia.</span></span></span></span>
作者
Ekundayo O. Ayegbusi
Akintunde O. Fehintola
Akinyosoye D. Ajiboye
Ayodele Idowu
Tope O. Okunola
Michael S. Archibong
Olajide E. Babalola
Olusegun O. Badejoko
Morebise O. Loto
Ekundayo O. Ayegbusi;Akintunde O. Fehintola;Akinyosoye D. Ajiboye;Ayodele Idowu;Tope O. Okunola;Michael S. Archibong;Olajide E. Babalola;Olusegun O. Badejoko;Morebise O. Loto(Department of Obstetrics, Gynaecology, and Perinatology, Faculty of Clinical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile Ife, Osun State. Nigeria;Department of Obstetrics and Gynaecology, State Specialist Hospital, Ikare Akoko, Ondo State, Nigeria;Department of Obstetrics and Gynaecology, Ekiti State University Teaching Hospital, Ado-Ekiti, Ekiti State, Nigeria)