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Pathologic Alterations of Canine and Feline Adrenal Glands

Pathologic Alterations of Canine and Feline Adrenal Glands
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摘要 The aim of the study was to determine the frequency and age-dependency of adrenal changes in dogs and cats, which were dissected between 2004 and 2006 at the Institute of Veterinary Pathology, LMU Munich. The adrenal glands of 101 dogs and 159 cats were dissected free from adjacent tissue, weighed, lamellated perpendicular to its longitudinal axis and were embedded in paraffin and plastic for histologic inspection. Ageing cats most frequently showed accessory cortical nodules in the capsule, cortex and medulla, pigment deposition and shock bodies. The appearance of accessory cortical nodules and pigment deposition were linked to the age of the cats and that of shock bodies was linked to infectious diseases. Inflammatory alterations were rare and neoplastic changes were not observed. In dogs, the most frequent alterations were accessory cortical nodules in the capsule, cortex and medulla and circulatory disturbances and there was a significant linkage of the appearance of cortical nodules and pigment deposition and age. Metabolic, inflammatory and tumorous diseases were rarely observed in the dogs examined. In summary, cats and dogs show similar incidental alterations of the adrenals. Clinical relevant adrenal lesions such as atrophy or primary neoplasia were rarely diagnosed. The aim of the study was to determine the frequency and age-dependency of adrenal changes in dogs and cats, which were dissected between 2004 and 2006 at the Institute of Veterinary Pathology, LMU Munich. The adrenal glands of 101 dogs and 159 cats were dissected free from adjacent tissue, weighed, lamellated perpendicular to its longitudinal axis and were embedded in paraffin and plastic for histologic inspection. Ageing cats most frequently showed accessory cortical nodules in the capsule, cortex and medulla, pigment deposition and shock bodies. The appearance of accessory cortical nodules and pigment deposition were linked to the age of the cats and that of shock bodies was linked to infectious diseases. Inflammatory alterations were rare and neoplastic changes were not observed. In dogs, the most frequent alterations were accessory cortical nodules in the capsule, cortex and medulla and circulatory disturbances and there was a significant linkage of the appearance of cortical nodules and pigment deposition and age. Metabolic, inflammatory and tumorous diseases were rarely observed in the dogs examined. In summary, cats and dogs show similar incidental alterations of the adrenals. Clinical relevant adrenal lesions such as atrophy or primary neoplasia were rarely diagnosed.
作者 Nadja Herbach Kirstin Wiele Ulrike Konietschke Walter Hermanns Nadja Herbach;Kirstin Wiele;Ulrike Konietschke;Walter Hermanns(Institute of Veterinary Pathology, Center for Clinical Veterinary Medicine of the Ludwig-Maximilians-University, Munich, Germany)
出处 《Open Journal of Pathology》 2016年第3期140-153,共14页 病理学期刊(英文)
关键词 ADRENAL HISTOLOGY DOG Cat Adrenal Histology Dog Cat
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