摘要
Juvenile systemic lupus erythematosus is a rare entity, affecting children under 16 years of age. Girls are more often affected than boys and the female predominance increases significantly with age. The initial manifestations are highly variable with an insidious and progressive onset. Non-specific symptoms include fever, anorexia, weight loss and asthenia. Pericarditis is the most common cardiac manifestation in systemic lupus erythematosus (SLE), occurring in 10% to 40% of cases. The biological elements of the diagnosis and follow-up of pediatric SLE are identical to those of adults and are based on regular measurement of complement, native anti-DNA antibodies, and inflammatory findings. Treatment is essentially based on corticosteroid therapy.
Juvenile systemic lupus erythematosus is a rare entity, affecting children under 16 years of age. Girls are more often affected than boys and the female predominance increases significantly with age. The initial manifestations are highly variable with an insidious and progressive onset. Non-specific symptoms include fever, anorexia, weight loss and asthenia. Pericarditis is the most common cardiac manifestation in systemic lupus erythematosus (SLE), occurring in 10% to 40% of cases. The biological elements of the diagnosis and follow-up of pediatric SLE are identical to those of adults and are based on regular measurement of complement, native anti-DNA antibodies, and inflammatory findings. Treatment is essentially based on corticosteroid therapy.
作者
Kalirou Traoré
Karamoko Sacko
Souleymane Mariko
Belco Maiga
Hawa Konaré
Adama Dembélé
Mohamed Cissé
Fousseyni Traoré
Ibrahim Dollo
Fatoumata Traore
Arouna Ouattara
Aminata Doumbia
Mamadou Traore
Djeneba Konate
Pierre Togo
Abdoul Karim Doumbia
Gassama Diaby
Abdoul Aziz Diakité
Ali Guindo
Fatoumata Dicko
Mariam Sylla
Boubacar Togo
Kalirou Traoré;Karamoko Sacko;Souleymane Mariko;Belco Maiga;Hawa Konaré;Adama Dembélé;Mohamed Cissé;Fousseyni Traoré;Ibrahim Dollo;Fatoumata Traore;Arouna Ouattara;Aminata Doumbia;Mamadou Traore;Djeneba Konate;Pierre Togo;Abdoul Karim Doumbia;Gassama Diaby;Abdoul Aziz Diakité;Ali Guindo;Fatoumata Dicko;Mariam Sylla;Boubacar Togo(Department of Pediatrics, Gabriel TOURE University Hospital, Bamoko, Mali;Guindo Clinic of Bamako, Bamoko, Mali;Mopti Hospital, Mopti, Mali;Reference Health Center of Commune V, Bamoko, Mali;Bamako Dermatology Hospital, Bamoko, Mali)
