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Ecthyma Gangrenosum in Patient with Bone Marrow Aplasia: A Case Report and Review of the Literature

Ecthyma Gangrenosum in Patient with Bone Marrow Aplasia: A Case Report and Review of the Literature
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摘要 Background: Ecthyma gangrenosum (EG) is an infrequent and discernible cutaneous disease caused by Pseudomonas aeruginosa. In situations where it is associated with septicemia in debilitated patients, the prognosis is usually unfavorable. Objective: In this case, we aim to verify risk factors, clinical, bacteriological and therapeutic characteristics of ecthyma gangrenosum and we review the literature to highlight the features of this rare condition and discuss the role of early diagnosis and treatment. Case Report: We describe the clinical case of a 4-year-old male with bone marrow aplasia who was presented with characteristic skin lesions of EG and developed sepsis later. Conclusion: EG is a cutaneous disease characterized by its aggressive nature. The presence of delayed diagnosis and therapy, along with sepsis, is closely linked to a high mortality rate. Treatment is empirically founded on an aggressive initial approach. Background: Ecthyma gangrenosum (EG) is an infrequent and discernible cutaneous disease caused by Pseudomonas aeruginosa. In situations where it is associated with septicemia in debilitated patients, the prognosis is usually unfavorable. Objective: In this case, we aim to verify risk factors, clinical, bacteriological and therapeutic characteristics of ecthyma gangrenosum and we review the literature to highlight the features of this rare condition and discuss the role of early diagnosis and treatment. Case Report: We describe the clinical case of a 4-year-old male with bone marrow aplasia who was presented with characteristic skin lesions of EG and developed sepsis later. Conclusion: EG is a cutaneous disease characterized by its aggressive nature. The presence of delayed diagnosis and therapy, along with sepsis, is closely linked to a high mortality rate. Treatment is empirically founded on an aggressive initial approach.
作者 Hanane Hajaj Hanae Bahari Hind Zahiri Ayyad Ghanam Aziza El Ouali Abdeladim Babakhouya Maria Rkain Hanane Hajaj;Hanae Bahari;Hind Zahiri;Ayyad Ghanam;Aziza El Ouali;Abdeladim Babakhouya;Maria Rkain(Department of Pediatrics, Mohammed VI University Hospital, Oujda, Morocco;Mohammed VI University Hospital, Medical School, Mohammed First University, Oujda, Morocco)
出处 《Open Journal of Pediatrics》 2024年第2期272-278,共7页 儿科学期刊(英文)
关键词 Ecthyma Gangrenosum CHILD Bone Marrow Aplasia Ecthyma Gangrenosum Child Bone Marrow Aplasia
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