摘要
Introduction: The hepatitis B virus (HBV) is one of the major causes of morbidity and mortality in the world. Few up-to-date data on this disease are available in developing countries, including Togo. The aim of this study was to estimate the prevalence of hepatitis B among women of childbearing age in the Kara region of Togo. Methods: A cross-sectional study was carried out from 23 to 25 September 2022 during a fairground campaign. Data were collected using a standardised questionnaire. HBV screening was performed using “SD-BIOLINE HBsAg WB” rapid immunochromatographic tests. HBV prevalence was reported with its 95% confidence interval (CI). Regression analyses were performed to identify factors associated with HBV infection. Results: A total of 327 women were enrolled, with a median age of 34 years and an interquartile range of [25 - 43]. Nearly half (49.5%) of the women had had their first sexual intercourse before the age of 18 and 2.1% had at least 2 sexual partners at the time of the survey. The majority (91.7%) had not used a condom the last time they had sex. The prevalence of hepatitis B was 10.4% (95% CI: 7.5 - 14.2]). In multivariable analysis, having had sexual intercourse for the first time after the age of 18 (ORa = 0.17;95% CI [0.06 - 0.43];p Conclusion: The results of this study underline the importance of monitoring the prevalence of hepatitis B in women of childbearing age, and of implementing targeted prevention and screening measures to eliminate mother-to-child transmission of HBV.
Introduction: The hepatitis B virus (HBV) is one of the major causes of morbidity and mortality in the world. Few up-to-date data on this disease are available in developing countries, including Togo. The aim of this study was to estimate the prevalence of hepatitis B among women of childbearing age in the Kara region of Togo. Methods: A cross-sectional study was carried out from 23 to 25 September 2022 during a fairground campaign. Data were collected using a standardised questionnaire. HBV screening was performed using “SD-BIOLINE HBsAg WB” rapid immunochromatographic tests. HBV prevalence was reported with its 95% confidence interval (CI). Regression analyses were performed to identify factors associated with HBV infection. Results: A total of 327 women were enrolled, with a median age of 34 years and an interquartile range of [25 - 43]. Nearly half (49.5%) of the women had had their first sexual intercourse before the age of 18 and 2.1% had at least 2 sexual partners at the time of the survey. The majority (91.7%) had not used a condom the last time they had sex. The prevalence of hepatitis B was 10.4% (95% CI: 7.5 - 14.2]). In multivariable analysis, having had sexual intercourse for the first time after the age of 18 (ORa = 0.17;95% CI [0.06 - 0.43];p Conclusion: The results of this study underline the importance of monitoring the prevalence of hepatitis B in women of childbearing age, and of implementing targeted prevention and screening measures to eliminate mother-to-child transmission of HBV.
作者
Gatibe Yendu-Suglpak Gnatou
Fatoumata Binta Tidiane Diallo
Fifonsi Adjidossi Gbeasor-Komlanvi
Sibabe Agoro
Arnold Junior Sadio
Latame Komla Adoli
Wendpouire Ida Carine Zida-Compaore
Yao Rodion Konu
Martin Kouame Tchankoni
Amegnona Agbonon
Didier Koumavi Ekouevi
Gatibe Yendu-Suglpak Gnatou;Fatoumata Binta Tidiane Diallo;Fifonsi Adjidossi Gbeasor-Komlanvi;Sibabe Agoro;Arnold Junior Sadio;Latame Komla Adoli;Wendpouire Ida Carine Zida-Compaore;Yao Rodion Konu;Martin Kouame Tchankoni;Amegnona Agbonon;Didier Koumavi Ekouevi(Department of Public Health, Faculty of Health Sciences, University of Lomé, Lomé, Togo;African Centre for Research in Epidemiology and Public Health (CARESP), Lomé, Togo;Togo Office, World Health Organization (WHO), Lomé, Togo;Center for Training and Research in Public Health, University of Lomé, Lomé, Togo;Ministry of Health, Public Hygiene and Universal Access to Health Care, Lomé, Togo;Laboratory of Pharmacology and Physiology, University of Lomé, Lomé, Togo;Institute of Public Health and Development, University of Bordeaux, Bordeaux, France)
