摘要
Joint pain is a real public health problem. According to recent studies, it is increasingly common in sub-Saharan Africa and represents a cause of greater loss of working days than accidents, heart disease and infections. The aim of this study was to study the pharmacochemical and therapeutic evidence of ten (10) plants used in the management of joint pain by traditional health practitioners in Ouagadougou. We conducted a meta-analysis of the data from December 2018 to September 2019. The anti-inflammatory activity of the ten (10) plants retained the maximum consensus internationally. Trichilia emetica Vahl (35.25%), Guiera senegalensis J.F.G.mel. (31%), Calotropis procera (Ait) Ait.F. (28.29%) and Crescientia cujete L. (25.12%) had more than 25% internationally reliability for their effects on joint pain. The structural analogy between conventional drugs and the molecules found in these plants has been confirmed. Additional studies should be carried out in order to improve and secure the use of these plants, which represent a prominent option in the therapeutic offer.
Joint pain is a real public health problem. According to recent studies, it is increasingly common in sub-Saharan Africa and represents a cause of greater loss of working days than accidents, heart disease and infections. The aim of this study was to study the pharmacochemical and therapeutic evidence of ten (10) plants used in the management of joint pain by traditional health practitioners in Ouagadougou. We conducted a meta-analysis of the data from December 2018 to September 2019. The anti-inflammatory activity of the ten (10) plants retained the maximum consensus internationally. Trichilia emetica Vahl (35.25%), Guiera senegalensis J.F.G.mel. (31%), Calotropis procera (Ait) Ait.F. (28.29%) and Crescientia cujete L. (25.12%) had more than 25% internationally reliability for their effects on joint pain. The structural analogy between conventional drugs and the molecules found in these plants has been confirmed. Additional studies should be carried out in order to improve and secure the use of these plants, which represent a prominent option in the therapeutic offer.
作者
Aminata P. Nacoulma
Gontili Reine Elodie Karambiri
Naamwin-So-Bawfu Romaric Meda
Mindiédiba Jean Bangou
Moussa Ouedraogo
Dieu-Donné Ouedraogo
Aminata P. Nacoulma;Gontili Reine Elodie Karambiri;Naamwin-So-Bawfu Romaric Meda;Mindiédiba Jean Bangou;Moussa Ouedraogo;Dieu-Donné Ouedraogo(Département des Sciences Pharmaceutiques Appliquées, UFR Sciences de la Santé, Université Joseph Ki-Zerbo, Ouagadougou, Burkina Faso;Training and Research Unit in Sciences and Technology (UFR-ST), Department of Biochemistry and Microbiology, University of Nazi BONI, Bobo-Dioulasso, Burkina Faso;Laboratory for Research and Education in Animal Health and Biotechnology (LARESBA), University of Nazi BONI, Bobo-Dioulasso, Burkina Faso;Département de Médecine et Spécialités Médicales, UFR Sciences de la Santé, Université Joseph Ki-Zerbo, Ouagadougou, Burkina Faso)
