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Clinical Trial of Medicinal Synthetic Aluminum-Magnesium Silicate (Antivirt<sup>&reg;</sup>) on Viral Loads and CD4-Lymphocytes Counts of HIV/AIDS Patients 被引量:1

Clinical Trial of Medicinal Synthetic Aluminum-Magnesium Silicate (Antivirt<sup>&reg;</sup>) on Viral Loads and CD4-Lymphocytes Counts of HIV/AIDS Patients
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摘要 For clinical trial of Medicinal synthetic Aluminum-magnesium silicate (MSAMS, Antivirt<sup>&reg;</sup>), on viral loads and CD4-lymphocytes counts of HIV/AIDS patients, 10 volunteers were treated. Their blood samples were tested for viral loads and for CD4-lymphocytes counts, before the treatment and every 4 weeks during the medication. The regimen was: MSAMS (50 mg/kg), MSAMS-stabilized Ampicillin trihydrate (7.5 mg/kg) and immunace extra protection<sup>&reg;</sup> (1 tablet/day), for 4 weeks. Then, it was reduced to 50 mg/kg (MSAMS) and the immune stimulant. When their viral loads become undetectable, they would be treated for additional 4 weeks. Initially, the Antivirt<sup>&reg;</sup>-regimen appeared to worsen both HIV infection-load and immune deficiency but later relieved them. Patients’ mean-viral load increased (P = 0.020), from 1820.30 ± 868.75 to 2855.90 ± 960.98, after 4 weeks before reducing (P = 0.030) to 1565.20 ± 743.17, after 8 weeks. Similarly, their mean-CD4-lymphocytes count reduced (P = 0.008) from 496.80 ± 194.39 to 263.90 ± 149.26, after 4 weeks before improving (P = 0.001) to 507.90 ± 133.19, after 8 weeks. For clinical trial of Medicinal synthetic Aluminum-magnesium silicate (MSAMS, Antivirt<sup>&reg;</sup>), on viral loads and CD4-lymphocytes counts of HIV/AIDS patients, 10 volunteers were treated. Their blood samples were tested for viral loads and for CD4-lymphocytes counts, before the treatment and every 4 weeks during the medication. The regimen was: MSAMS (50 mg/kg), MSAMS-stabilized Ampicillin trihydrate (7.5 mg/kg) and immunace extra protection<sup>&reg;</sup> (1 tablet/day), for 4 weeks. Then, it was reduced to 50 mg/kg (MSAMS) and the immune stimulant. When their viral loads become undetectable, they would be treated for additional 4 weeks. Initially, the Antivirt<sup>&reg;</sup>-regimen appeared to worsen both HIV infection-load and immune deficiency but later relieved them. Patients’ mean-viral load increased (P = 0.020), from 1820.30 ± 868.75 to 2855.90 ± 960.98, after 4 weeks before reducing (P = 0.030) to 1565.20 ± 743.17, after 8 weeks. Similarly, their mean-CD4-lymphocytes count reduced (P = 0.008) from 496.80 ± 194.39 to 263.90 ± 149.26, after 4 weeks before improving (P = 0.001) to 507.90 ± 133.19, after 8 weeks.
作者 Maduike C. O. Ezeibe Dahiru Aleeyu Ijeoma J. Ogbonna Ekenma Kalu Maduike C. O. Ezeibe;Dahiru Aleeyu;Ijeoma J. Ogbonna;Ekenma Kalu(College of Veterinary Medicine, Michael Okpara University of Agriculture, Umudike, Nigeria;Basic Health Clinic, Abuja, Nigeria)
出处 《World Journal of AIDS》 2016年第2期37-41,共5页 艾滋病(英文)
关键词 Antivirt<sup>®</sup> Nanoparticles Destroying Infected Cells Unmasking “Hidden Infections” Mopping-Out HIV Antivirt<sup>®</sup> Nanoparticles Destroying Infected Cells Unmasking “Hidden Infections” Mopping-Out HIV
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