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Acute Coronary Syndromes in Elderly: Multicentric Study about 76 Cases in 3 Cardiology Departments in Dakar

Acute Coronary Syndromes in Elderly: Multicentric Study about 76 Cases in 3 Cardiology Departments in Dakar
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摘要 <strong>Background:</strong> <span style="white-space:normal;font-size:10pt;font-family:;" "="">Acute coronary syndromes (ACS) in the elderly are often a problem in their diagnosis and treatment, explaining a high mortality. Our study aimed to evaluate diagnostic, therapeutic and evolutive aspects in 3 cardiology departments of Dakar. <b>Patients and Methods: </b>We conducted a multicentric, retrospective and descriptive study during 2 years from January 1</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">,</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">2017 </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">to December 31</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">, 2018</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">. All patients older than 75 years admitted for acute coronary syndromes were included. The diagnosis was based on clinical signs with typical electrocardiographic changes and troponin assays. <b>Results: </b>Seventy and six patients (76) were enrolled. The prevalence of ACS in the elderly was 2.5% of all hospitalized patients and 21.8% of all ACS. The average age was 78.76 years. The sex ratio male/female was 1.71. The cardiovascular risk factors were essentially physical inactivity (97%) and hypertension (6.84%). Angina pain was the master symptom, but the pain was atypical in the most cases (52.63%). The second sign was dyspnea (46.05%). The average admission time for patients with STEMI (ST-segment elevation myocardial infarction) was 27 hours. Among these patients, 67% had a STEMI, 24% had NSTEMI (non-ST segment elevation myocardial infarction) and 9% had an unstable angina. Four patients had a thrombolysis with an average time of 5.75 hours. The thrombolysis was not successful for all patients. Eighteen (18) patients had a percutaneous coronary intervention (PCI), but only two had a primary PCI. DES (drug-eluting-stents) were the most used stents (55</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">.</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">5%). Eighty and nine (89%) of PCI were successful. Complications were essentially hemodynamic and rhythmic (26.6%). In-hospital mortality was 14.47%;n = 11. <b>Conclusion: </b>Our study revealed a delay in diagnosis and management of ACS in the elderly. Reperfusion therapy was less practiced in our context and the prognosis was poorer with a high mortality.</span> <strong>Background:</strong> <span style="white-space:normal;font-size:10pt;font-family:;" "="">Acute coronary syndromes (ACS) in the elderly are often a problem in their diagnosis and treatment, explaining a high mortality. Our study aimed to evaluate diagnostic, therapeutic and evolutive aspects in 3 cardiology departments of Dakar. <b>Patients and Methods: </b>We conducted a multicentric, retrospective and descriptive study during 2 years from January 1</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">,</span><span style="white-space:normal;font-size:10pt;font-family:;" "=""> </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">2017 </span><span style="white-space:normal;font-size:10pt;font-family:;" "="">to December 31</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">, 2018</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">. All patients older than 75 years admitted for acute coronary syndromes were included. The diagnosis was based on clinical signs with typical electrocardiographic changes and troponin assays. <b>Results: </b>Seventy and six patients (76) were enrolled. The prevalence of ACS in the elderly was 2.5% of all hospitalized patients and 21.8% of all ACS. The average age was 78.76 years. The sex ratio male/female was 1.71. The cardiovascular risk factors were essentially physical inactivity (97%) and hypertension (6.84%). Angina pain was the master symptom, but the pain was atypical in the most cases (52.63%). The second sign was dyspnea (46.05%). The average admission time for patients with STEMI (ST-segment elevation myocardial infarction) was 27 hours. Among these patients, 67% had a STEMI, 24% had NSTEMI (non-ST segment elevation myocardial infarction) and 9% had an unstable angina. Four patients had a thrombolysis with an average time of 5.75 hours. The thrombolysis was not successful for all patients. Eighteen (18) patients had a percutaneous coronary intervention (PCI), but only two had a primary PCI. DES (drug-eluting-stents) were the most used stents (55</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">.</span><span style="white-space:normal;font-size:10pt;font-family:;" "="">5%). Eighty and nine (89%) of PCI were successful. Complications were essentially hemodynamic and rhythmic (26.6%). In-hospital mortality was 14.47%;n = 11. <b>Conclusion: </b>Our study revealed a delay in diagnosis and management of ACS in the elderly. Reperfusion therapy was less practiced in our context and the prognosis was poorer with a high mortality.</span>
作者 Momar Dioum Papa Nguirane Ndiaye Cheikh Gaye Yande C. Faye Joseph Salvador Mingou Bouna Diack Dominique I. Bindia Alassane Mbaye Maboury Diao Momar Dioum;Papa Nguirane Ndiaye;Cheikh Gaye;Yande C. Faye;Joseph Salvador Mingou;Bouna Diack;Dominique I. Bindia;Alassane Mbaye;Maboury Diao(Cardiology Department CHU FANN, Dakar, Senegal;Hoggy Cardiology Department, Dakar, Senegal;Cardiology Department CHU Aristide Le Dantec, Dakar, Senegal)
出处 《World Journal of Cardiovascular Diseases》 2021年第12期610-618,共9页 心血管病(英文)
关键词 Acute Coronary Syndromes ELDERLY DAKAR Senegal Acute Coronary Syndromes Elderly Dakar Senegal
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