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SFET Based Immunosensor

SFET Based Immunosensor
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摘要 A new design of an immunosensor for viral molecules based on the ISFET nanoscale structure has been proposed. Physical processes take place inimmunosensor are modeled. The effect of modulation of the surface potential of the interface between a semiconductor depleted layer (channel) and a dielectric during the interaction and immobilization of viral molecules was used. Analytical expression for the source-drain current of ISFET as a function of virus types and concentration is presented and analyzed. Dependency of the source-drain current vs. concentration of viruses is analyzed for the COVID-19 virus. A new design of an immunosensor for viral molecules based on the ISFET nanoscale structure has been proposed. Physical processes take place inimmunosensor are modeled. The effect of modulation of the surface potential of the interface between a semiconductor depleted layer (channel) and a dielectric during the interaction and immobilization of viral molecules was used. Analytical expression for the source-drain current of ISFET as a function of virus types and concentration is presented and analyzed. Dependency of the source-drain current vs. concentration of viruses is analyzed for the COVID-19 virus.
作者 Ferdinand Gasparyan Lusine Gasparyan Vahan Simonyan Ferdinand Gasparyan;Lusine Gasparyan;Vahan Simonyan(Yerevan State University, Yerevan, Armenia;DNA-HIVE LLC, Rockville, MD, USA)
出处 《Open Journal of Biophysics》 CAS 2022年第4期223-233,共11页 生物物理学期刊(英文)
关键词 BIOSENSOR ISFET ANTIBODY VIRUS Sensitivity Biosensor ISFET Antibody Virus Sensitivity
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