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Mesenchymal stem cells for the treatment of tendon disorders

Mesenchymal stem cells for the treatment of tendon disorders
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摘要 Tendon disorders are associated with increased morbidity and a reduction in the quality of life, especially in people of working age. Recently, a new approach, cell-based therapy, offers promising potential to treat tendon injuries. Mesenchymal stem cells are the most suitable candidates for such therapies due to their capacity to differentiate into cells of mesodermal origin, their paracrine properties and their potential use in autologous transplantation. This review summarizes experimental as well as clinical data focusing on the use of mesenchymal stem cells to treat tendinophaties. Tendon disorders are associated with increased morbidity and a reduction in the quality of life, especially in people of working age. Recently, a new approach, cell-based therapy, offers promising potential to treat tendon injuries. Mesenchymal stem cells are the most suitable candidates for such therapies due to their capacity to differentiate into cells of mesodermal origin, their paracrine properties and their potential use in autologous transplantation. This review summarizes experimental as well as clinical data focusing on the use of mesenchymal stem cells to treat tendinophaties.
作者 Lucia Machová Urdzíková Petr Lesny Eva Syková Pavla Jendelová
机构地区 Institute of Experimental Medicine Institute of Experimental Medicine
出处 《Journal of Biomedical Science and Engineering》 2013年第8期14-23,共10页 生物医学工程（英文）
关键词 Tendinophaty TENDINOSIS TENDONITIS Models of TENDON Injuries Mesenchymal Stem Cells ROTATOR CUFF ACHILLES TENDON TENDON Rupture Tendinophaty Tendinosis Tendonitis Models of Tendon Injuries Mesenchymal Stem Cells Rotator Cuff Achilles Tendon Tendon Rupture
分类号 R73 [医药卫生—肿瘤]
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共引文献81

Journal of Biomedical Science and Engineering
2013年 第8期

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