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Protein Drug-Loaded Polymeric Nanoparticles

Protein Drug-Loaded Polymeric Nanoparticles
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摘要 Considerable interest and research have focused on the administration of therapeutic proteins. For delivery of therapeutic proteins, bioavailability and stabilization of protein drugs to maintain therapeutically acceptable levels is an important challenge in clinical trials. To overcome these challenges, polymeric nanoparticles have become one of the best methods for protein delivery. In this review, we summarize the current available polymeric nanoparticles designed for protein delivery, current status, and advantages of protein delivery systems. Considerable interest and research have focused on the administration of therapeutic proteins. For delivery of therapeutic proteins, bioavailability and stabilization of protein drugs to maintain therapeutically acceptable levels is an important challenge in clinical trials. To overcome these challenges, polymeric nanoparticles have become one of the best methods for protein delivery. In this review, we summarize the current available polymeric nanoparticles designed for protein delivery, current status, and advantages of protein delivery systems.
出处 《Journal of Biomedical Science and Engineering》 2014年第10期825-832,共8页 生物医学工程(英文)
关键词 POLYMERIC NANOPARTICLES PROTEINS DRUG Delivery Polymeric Nanoparticles Proteins Drug Delivery
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