摘要
Peripheral oxygenation level (SpO<sub>2</sub>) can provide vital information on body functions. Continuous monitoring facilitates effective diagnosis and treatment and can even be lifesaving. Clinical device monitor SpO<sub>2</sub> using a clip, and measure light transmission through the tissue. This method limits the body locations of the clip’s placement and is sensitive to body movement, which hampers continuous SpO<sub>2</sub> monitoring during wakefulness or sleep, thus decreasing its usability in clinics and its accessibility in homecare usage. We developed a portable, wireless, flat and low cost prototype for continuous monitoring of SpO<sub>2</sub> that overcomes those limitations. The prototype enables convenient measurement in larger variety of body locations by spectrophotometric measurements of changes in the optical reflectance unlike other device that measure absorption through the tissue. The original design and signal processing enable reliable signal acquisition, synchronization and control. An Android’s application was developed to provide a user friendly interface for results display on smartphones. The prototype’s measurements were compared to commercial device that simultaneously measured heart rate frequency, transcutaneous oxygen tension (tcPO<sub>2</sub>) and SpO<sub>2</sub>. The prototype’s measurements accurately reflected changes caused by blood pulses, were correlated to the heart rate, and were sensitive to changes in oxygen saturation. Excellent real time behavior and synchronization were demonstrated between the hardware and smartphone software. Our prototype thus enables convenient SpO<sub>2</sub> measurement over the entire body, while maintaining accuracy comparable to commercial device. Its smartphone application enables accessible and understandable results display to patients, care-givers and healthcare professionals. The application’s display and alert calibration flexibility facilitates the prototype’s usage in changing medical requirements and for various disease and conditions. A device based on this prototype can monitor continuously and accurately patients’ SpO<sub>2</sub> without limiting their everyday activities or disturbing their sleep and can thus significantly im-prove their medical care in both clinics and home.
Peripheral oxygenation level (SpO<sub>2</sub>) can provide vital information on body functions. Continuous monitoring facilitates effective diagnosis and treatment and can even be lifesaving. Clinical device monitor SpO<sub>2</sub> using a clip, and measure light transmission through the tissue. This method limits the body locations of the clip’s placement and is sensitive to body movement, which hampers continuous SpO<sub>2</sub> monitoring during wakefulness or sleep, thus decreasing its usability in clinics and its accessibility in homecare usage. We developed a portable, wireless, flat and low cost prototype for continuous monitoring of SpO<sub>2</sub> that overcomes those limitations. The prototype enables convenient measurement in larger variety of body locations by spectrophotometric measurements of changes in the optical reflectance unlike other device that measure absorption through the tissue. The original design and signal processing enable reliable signal acquisition, synchronization and control. An Android’s application was developed to provide a user friendly interface for results display on smartphones. The prototype’s measurements were compared to commercial device that simultaneously measured heart rate frequency, transcutaneous oxygen tension (tcPO<sub>2</sub>) and SpO<sub>2</sub>. The prototype’s measurements accurately reflected changes caused by blood pulses, were correlated to the heart rate, and were sensitive to changes in oxygen saturation. Excellent real time behavior and synchronization were demonstrated between the hardware and smartphone software. Our prototype thus enables convenient SpO<sub>2</sub> measurement over the entire body, while maintaining accuracy comparable to commercial device. Its smartphone application enables accessible and understandable results display to patients, care-givers and healthcare professionals. The application’s display and alert calibration flexibility facilitates the prototype’s usage in changing medical requirements and for various disease and conditions. A device based on this prototype can monitor continuously and accurately patients’ SpO<sub>2</sub> without limiting their everyday activities or disturbing their sleep and can thus significantly im-prove their medical care in both clinics and home.
作者
Zehava Ovadia-Blechman
Omri Gino
Liron Dandeker
Nadav Sheffer
Erik Baltaxe
Vered Aharonson
Zehava Ovadia-Blechman;Omri Gino;Liron Dandeker;Nadav Sheffer;Erik Baltaxe;Vered Aharonson(Medical Engineering Department, Afeka Tel-Aviv Academic College of Engineering, Tel Aviv, Israel;Electrical Engineering Department, Afeka Tel-Aviv Academic College of Engineering, Tel Aviv, Israel;Pulmonary Diseases and Internal Medicine Institute, Sheba Medical Center, Tel Hashomer, Israel;School of Electrical and Information Engineering, University of the Witwatersrand, Johannesburg, South Africa)
