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Combined Use of k-Mer Numerical Features and Position-Specific Categorical Features in Fixed-Length DNA Sequence Classification

Combined Use of k-Mer Numerical Features and Position-Specific Categorical Features in Fixed-Length DNA Sequence Classification
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摘要 To classify DNA sequences, k-mer frequency is widely used since it can convert variable-length sequences into fixed-length and numerical feature vectors. However, in case of fixed-length DNA sequence classification, subsequences starting at a specific position of the given sequence can also be used as categorical features. Through the performance evaluation on six datasets of fixed-length DNA sequences, our algorithm based on the above idea achieved comparable or better performance than other state-of-the art algorithms. To classify DNA sequences, k-mer frequency is widely used since it can convert variable-length sequences into fixed-length and numerical feature vectors. However, in case of fixed-length DNA sequence classification, subsequences starting at a specific position of the given sequence can also be used as categorical features. Through the performance evaluation on six datasets of fixed-length DNA sequences, our algorithm based on the above idea achieved comparable or better performance than other state-of-the art algorithms.
出处 《Journal of Biomedical Science and Engineering》 2017年第8期390-401,共12页 生物医学工程(英文)
关键词 Sequence CLASSIFICATION NUMERICAL and CATEGORICAL FEATURES Feature Selection Sequence Classification Numerical and Categorical Features Feature Selection
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