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Family tree and population: Distinction and similarity of the analysis on example of hemophilia

Family tree and population: Distinction and similarity of the analysis on example of hemophilia
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摘要 On the basis of Hardy-Weinberg law the distinction in the philosophy of the description of a family tree and a population is considered. With the help of introduction of the equivalent constant mutagen factor both in a family tree and in a population, the analysis of hemophilia is led. Influence of selection at presence of hemophilia is considered. On the basis of idea of Danforth and Haldane about the balance mutagenesis and selection at presence of hemophilia, the inter-relation of selection parameter and the equivalent constant mutagen factor is found. It is shown, that dynamics of development of hemophilia in a family tree and in population are similar. On the basis of Hardy-Weinberg law the distinction in the philosophy of the description of a family tree and a population is considered. With the help of introduction of the equivalent constant mutagen factor both in a family tree and in a population, the analysis of hemophilia is led. Influence of selection at presence of hemophilia is considered. On the basis of idea of Danforth and Haldane about the balance mutagenesis and selection at presence of hemophilia, the inter-relation of selection parameter and the equivalent constant mutagen factor is found. It is shown, that dynamics of development of hemophilia in a family tree and in population are similar.
出处 《Natural Science》 2013年第9期979-986,共8页 自然科学期刊(英文)
关键词 Alleles Equivalent Constant MUTAGEN Factor Family Tree POPULATION HEMOPHILIA Balance of Selection and MUTAGENESIS Alleles Equivalent Constant Mutagen Factor Family Tree Population Hemophilia Balance of Selection and Mutagenesis
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