摘要
Nowadays, the fast development of nanobiotechnology, has led to rapid diagnosis of important infectious diseases such as arboviruses-borne diseases, vector-borne infections and waterborne parasites diseases and others in order to reduce and avoid further dissemination of the infections within the general population. Furthermore, new nanomedicines based on the application of silver and gold nanoparticles which are less toxic, more effective, and that does not generate resistance could help to solve the problems of parasitic disease like leishmaniasis and chagas disease. It turns out that the combination of nanoparticles with antibiotics not only reduces the toxicity of both agents towards human cells but also enhances their ability to destroy bacteria by facilitating the binding of antibiotics to the microbes. Moreover, combining nanoparticles with antimicrobial peptides and essential oils with nanoparticles generates genuine synergy against microbial resistance.
Nowadays, the fast development of nanobiotechnology, has led to rapid diagnosis of important infectious diseases such as arboviruses-borne diseases, vector-borne infections and waterborne parasites diseases and others in order to reduce and avoid further dissemination of the infections within the general population. Furthermore, new nanomedicines based on the application of silver and gold nanoparticles which are less toxic, more effective, and that does not generate resistance could help to solve the problems of parasitic disease like leishmaniasis and chagas disease. It turns out that the combination of nanoparticles with antibiotics not only reduces the toxicity of both agents towards human cells but also enhances their ability to destroy bacteria by facilitating the binding of antibiotics to the microbes. Moreover, combining nanoparticles with antimicrobial peptides and essential oils with nanoparticles generates genuine synergy against microbial resistance.
作者
Wafaa M. Hikal
Amra Bratovcic
Rowida S. Baeshen
Kirill G. Tkachenko
Hussein A. H. Said-Al Ahl
Wafaa M. Hikal;Amra Bratovcic;Rowida S. Baeshen;Kirill G. Tkachenko;Hussein A. H. Said-Al Ahl(Department of Biology, Faculty of Science, University of Tabuk, Tabuk, KSA;Water Pollution Research Department, Environmental Research Division, National Research Centre, Giza, Egypt;Department of Physical Chemistry and Electrochemistry, Faculty of Technology, University of Tuzla, Tuzla, Bosnia and Herzegovina;V. L. Komarov Botanical Institute of the Russian Academy of Sciences, Saint Petersburg, Russia;Medicinal and Aromatic Plants Research Department, National Research Centre, Giza, Egypt)
