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Universal RNA editing in a human liver at the fetal stage

Universal RNA editing in a human liver at the fetal stage
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摘要 It is known that RNA editing occurs in human cells, which can change the information transmission from DNA to RNA and proteins. Most previous studies have focused on editing of the mRNAs. Here we reported that several kinds of RNAs, including miRNA, rRNA, mRNA, miscRNA and unknown RNA, exhibited base editing in a human fetal liver. Several editing types are displayed. Our data reveals that RNA editing may occur in different species of RNAs. It is known that RNA editing occurs in human cells, which can change the information transmission from DNA to RNA and proteins. Most previous studies have focused on editing of the mRNAs. Here we reported that several kinds of RNAs, including miRNA, rRNA, mRNA, miscRNA and unknown RNA, exhibited base editing in a human fetal liver. Several editing types are displayed. Our data reveals that RNA editing may occur in different species of RNAs.
出处 《Open Journal of Genetics》 2012年第3期163-166,共4页 遗传学期刊(英文)
关键词 RNA EDITING miRNA RRNA mRNA miscRNA FETAL LIVER RNA Editing miRNA rRNA mRNA miscRNA Fetal Liver
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