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Combination Effect of Miconazole with Polygodial against <i>Candida albicans</i>

Combination Effect of Miconazole with Polygodial against <i>Candida albicans</i>
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摘要 The combination effect of miconazole with polygodial against Candida albicans was investigated by an in vitro checkerboard method. Isobolograms, fractional inhibitory concentration (FIC), and fractional fungicidal concentration (FFC) indices were used for evaluating the interaction between compounds combined. The combination of miconazole with polygodial exhibited strong synergism on both fungistatic and fungicidal action against this opportunistic pathogen. The combination effect of miconazole with polygodial against Candida albicans was investigated by an in vitro checkerboard method. Isobolograms, fractional inhibitory concentration (FIC), and fractional fungicidal concentration (FFC) indices were used for evaluating the interaction between compounds combined. The combination of miconazole with polygodial exhibited strong synergism on both fungistatic and fungicidal action against this opportunistic pathogen.
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出处 《Open Journal of Medical Microbiology》 2011年第1期7-11,共5页 医学微生物学(英文)
关键词 Polygodial MICONAZOLE CANDIDA ALBICANS COMBINATION Synergism Polygodial Miconazole Candida albicans Combination Synergism
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