摘要
Background: Toxoplasmosis had a remarked role in disturbing pregnancy in women by abortions and congenital abnormalities outcome .Vitamin D deficiency had a role in bone fragility, osteoporosis, exposing women to fractures as well as to bone deformities in newborns. Objective: To assess the relationship between toxoplasmosis seropositivity and vitamin D abnormalities in sera of women in childbearing ages using ELISA and auto-analyzers. Methodology: A cross-sectional study was conducted by examining the sera of 153 women, who visited Azadi Teaching Hospital Gynecological and Obstetric Clinics. Their complaints involve signs of bad obstetric history (BOH) and bone disorders, versus to 46 women negative for (BOH). Their ages ranged from 15 to 50 years. The results: The overall rate of positive toxoplasmosis was 78.43% distributed into the following rates: 22.87%, 49.01%, and 13.07% for IgM, IgG, and IgM + IgG antibodies, P T. gondii IgM than in sera of women aged over 46 years, P Conclusions: The rate of toxoplasmosis among childbearing age women was high, and the relationship between toxoplasmosis and vitamin D deficiency was significant. This finding is preliminary and prone women for getting osteoporosis.
Background: Toxoplasmosis had a remarked role in disturbing pregnancy in women by abortions and congenital abnormalities outcome .Vitamin D deficiency had a role in bone fragility, osteoporosis, exposing women to fractures as well as to bone deformities in newborns. Objective: To assess the relationship between toxoplasmosis seropositivity and vitamin D abnormalities in sera of women in childbearing ages using ELISA and auto-analyzers. Methodology: A cross-sectional study was conducted by examining the sera of 153 women, who visited Azadi Teaching Hospital Gynecological and Obstetric Clinics. Their complaints involve signs of bad obstetric history (BOH) and bone disorders, versus to 46 women negative for (BOH). Their ages ranged from 15 to 50 years. The results: The overall rate of positive toxoplasmosis was 78.43% distributed into the following rates: 22.87%, 49.01%, and 13.07% for IgM, IgG, and IgM + IgG antibodies, P T. gondii IgM than in sera of women aged over 46 years, P Conclusions: The rate of toxoplasmosis among childbearing age women was high, and the relationship between toxoplasmosis and vitamin D deficiency was significant. This finding is preliminary and prone women for getting osteoporosis.
