摘要
<strong>Objective: </strong>The present was initiated to study the antibacterial properties of the <i>Crateva adansonii</i> DC extract on germs commonly identified in skin and digestive infections in Benin as well as the reversion of resistance to these aforementioned germs. <strong>Method: </strong>The bacteria’s sensitivity test to extracts was carried out by the microdilution method in liquid medium as well as the MIC and the reversion of bacterial resistance. For the determination of the MBC, this technique is used coupled with spreading on agar medium. <strong>Results: </strong>The results show an antibacterial activity of the extract with MICs between 0.625 - 5 mg/ml. The CMB of <i>Enterococcus faecalis</i> ATCC 29212 is 2.5 mg/ml while that of Methicillin-resistant <i>Staphylococcus aureus</i> and <i>Staphylococcus epidermidis</i> CIP 8039 is 5 mg/ml. The reversion of bacterial resistance has shown a synergy of action between our extract and conventional antibiotics.
<strong>Objective: </strong>The present was initiated to study the antibacterial properties of the <i>Crateva adansonii</i> DC extract on germs commonly identified in skin and digestive infections in Benin as well as the reversion of resistance to these aforementioned germs. <strong>Method: </strong>The bacteria’s sensitivity test to extracts was carried out by the microdilution method in liquid medium as well as the MIC and the reversion of bacterial resistance. For the determination of the MBC, this technique is used coupled with spreading on agar medium. <strong>Results: </strong>The results show an antibacterial activity of the extract with MICs between 0.625 - 5 mg/ml. The CMB of <i>Enterococcus faecalis</i> ATCC 29212 is 2.5 mg/ml while that of Methicillin-resistant <i>Staphylococcus aureus</i> and <i>Staphylococcus epidermidis</i> CIP 8039 is 5 mg/ml. The reversion of bacterial resistance has shown a synergy of action between our extract and conventional antibiotics.
作者
Zinsou Franck Mignanwandé
Roch Christian Johnson
Armelle Sabine Yélignan Hounkpatin
Gratien Boni
Armel Géraldo Houndeton
Eustache Enock Houéto
Wilfrid Hinnoutondji Kpètèhoto
Madjid Olatoundé Amoussa
Zinsou Franck Mignanwandé;Roch Christian Johnson;Armelle Sabine Yélignan Hounkpatin;Gratien Boni;Armel Géraldo Houndeton;Eustache Enock Houéto;Wilfrid Hinnoutondji Kpètèhoto;Madjid Olatoundé Amoussa(Interfaculty Center for Training and Research in Environment for Sustainable Development (CIFRED), University of Abomey-Calavi, Abomey-Calavi, Benin;Technical Higher Teacher Training School (ENSET), National University of Sciences, Technologies, Engineering and Mathematics (UNSTIM), Abomey, Benin;Faculty of Sciences and Technology, University of Abomey-Calavi, Abomey-Calavi, Benin)
