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Phytochemical Analysis and Bioactivity Screening of Primary and Secondary Metabolic Products of Medicinal Plants in the Valleys of Medina Region Saudi Arabia

Phytochemical Analysis and Bioactivity Screening of Primary and Secondary Metabolic Products of Medicinal Plants in the Valleys of Medina Region Saudi Arabia
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摘要 Medicinal plants are highly valued for their active compounds. These plants can be used in various fields and preservation of these plants in their environment. The present study aimed to screen medicinal plants used in traditional medicine in Medina valleys for the presence of metabolites, and to answer the following question: is the ethnomedicinal importance of medicinal plants used in Medina valleys conform to their primary and secondary metabolite content. Eight plants (Pulicaria incise, Heliotropium arbainense, Commicarpus grandiflorus, Rumex vesicarius, Senna alexandrina, Rhazya stricta, Withania somnifera and Asphodelus fistulosus) were collected from the Medina valleys and were biochemically analyzed to determine the different compounds after leaves extraction analyzed statistically to clarify the content of primary compounds. The chemical compounds in the most active fraction were determined using quantitative phytochemical and gas chromatography-mass spectrometry (GC/MS) analytical methods, comparing the mass spectra of the GC/MS identified compounds with those of the Center of Excellence in Environmental Studies (CEES) database library. The result showed 16 aroma compounds representing the GC/MS analysis revealed the presence of various compounds like 4,4-Dimethyl octane, 5H-1-Pyrindine and 1,3- Cyclopentadiene, 1,2,5,5-tetramethyl- in the ethanolic extract of Pulicaria incisa. The most prevalent plants were Pulicaria incisa, Senna alexandrina and Heliotropium arbainense the study plants have high content of protein. There is a need to focus phytochemical screening on ethnobotanical studies to complete research into traditional medicine which leads to the discovery of new drugs. Medicinal plants are highly valued for their active compounds. These plants can be used in various fields and preservation of these plants in their environment. The present study aimed to screen medicinal plants used in traditional medicine in Medina valleys for the presence of metabolites, and to answer the following question: is the ethnomedicinal importance of medicinal plants used in Medina valleys conform to their primary and secondary metabolite content. Eight plants (Pulicaria incise, Heliotropium arbainense, Commicarpus grandiflorus, Rumex vesicarius, Senna alexandrina, Rhazya stricta, Withania somnifera and Asphodelus fistulosus) were collected from the Medina valleys and were biochemically analyzed to determine the different compounds after leaves extraction analyzed statistically to clarify the content of primary compounds. The chemical compounds in the most active fraction were determined using quantitative phytochemical and gas chromatography-mass spectrometry (GC/MS) analytical methods, comparing the mass spectra of the GC/MS identified compounds with those of the Center of Excellence in Environmental Studies (CEES) database library. The result showed 16 aroma compounds representing the GC/MS analysis revealed the presence of various compounds like 4,4-Dimethyl octane, 5H-1-Pyrindine and 1,3- Cyclopentadiene, 1,2,5,5-tetramethyl- in the ethanolic extract of Pulicaria incisa. The most prevalent plants were Pulicaria incisa, Senna alexandrina and Heliotropium arbainense the study plants have high content of protein. There is a need to focus phytochemical screening on ethnobotanical studies to complete research into traditional medicine which leads to the discovery of new drugs.
作者 Safa Alsaedi Ghalia Aljeddani Safa Alsaedi;Ghalia Aljeddani(Department of Biology, Collage of Science, University of Jeddah, Jeddah, Saudi Arabia)
机构地区 Department of Biology
出处 《Advances in Biological Chemistry》 CAS 2022年第4期92-115,共24页 生物化学进展(英文)
关键词 C Phytochemical Medicinal Plants GC-MS Analysis Primary and Secondary Metabolic C Phytochemical Medicinal Plants GC-MS Analysis Primary and Secondary Metabolic
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  • 1姚新生.天然药物化学:第二版[M].北京:人民卫生出版社,1995.241.
  • 2韩驰.茶叶防癌有效成份及其作用机理[J].中国药理学与毒理学杂志,1997,11(2):105-105. 被引量:12
  • 3NO J K, et al. Inhibition of tyrosinase by green tea components. Life sciences, 1999,65 ( 21 ) : 241.
  • 4Sakaguchi N, et al. Reactive oxygen species and intracellular Ca2+ , common signals for apoptosis induced by gallic acid. Biochemical Pharmacology, 1998,55 (12) : 1973( Biochem Pharmacol).
  • 5Inoue M, et al. Role fo reactive oxygen species in gallic acid-induced apoptosis. Biological & Pharmaceutical Bulletin, 2000,23(10): 1153.
  • 6Yang L L, et al. Induction of apoptosis by hydrolyzable tannins from Eugenia jambos L. on human leukemia cells.Cancer Letters, 2000,157( 1 ) : 65.
  • 7Chen P S, et al. Folk medicine Terminalia catappa and its major tannin component, punicalagin, are effective against bleomycin-induced genotoxicity in Chinese hamster ovary cells. Cancer Letters, 2000,152:115.
  • 8Pan M H, et al. Induction of apoptosis by penta-O-galloyl-β-D-glucose through activation of caspase-3 in human leukemia HL-60 cells. European Journal of Pharmacology,1999,381:171.
  • 9Lee M H, et al. EBV DNA polymerase inhibition of tannins from Eugenia uniflora. Cancer letters, 2000,154:131.
  • 10Aoki K, et al. A maeroeireular ellagitannin, oenothein-B,suppresses mouse mammary-tumor gene-expression via inhibition of poly ( ADP-ribose ) glycohydrolase. Biochem Bioph Res, 1995, 210(2):329.

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