摘要
Antibacterial activity of methanol, n-hexane and water extracts of seeds and bark of Moringa oleifera and Moringa ovalifolia was conducted. The causative agents of common bacterial infections that are thought to cause water-borne diseases, namely, Escherichia coli, Enterococcus faecalis, and Bacillus cereus were chosen for the study. The paper-disc diffusion method was used with treatments arranged in a completely randomized design and replicated four times. The M. oleifera extracts showed more inhibitory effect than those of M. ovolifolia. The conventional antibiotic Ampicilin generally showed higher inhibitory effect than the extracts of both M. oleifera and M. ovalifolia. The inhibitory effect varied depending on the solvent used. The n-hexane extracts of both seeds and bark of M. ovalifolia and M. oleifera had almost the same inhibition activities (6 ± 1 mm mean inhibition zones) on B. cereus, E. coli and E. faecalis. The n-hexane extract generally gave lower antibacterial activities than those of the other solvents for seeds and back. The results of the study showed that M. oleifera and M. ovalifolia had a degree of antibacterial properties against the selected test organisms that cause water borne diseases.
Antibacterial activity of methanol, n-hexane and water extracts of seeds and bark of Moringa oleifera and Moringa ovalifolia was conducted. The causative agents of common bacterial infections that are thought to cause water-borne diseases, namely, Escherichia coli, Enterococcus faecalis, and Bacillus cereus were chosen for the study. The paper-disc diffusion method was used with treatments arranged in a completely randomized design and replicated four times. The M. oleifera extracts showed more inhibitory effect than those of M. ovolifolia. The conventional antibiotic Ampicilin generally showed higher inhibitory effect than the extracts of both M. oleifera and M. ovalifolia. The inhibitory effect varied depending on the solvent used. The n-hexane extracts of both seeds and bark of M. ovalifolia and M. oleifera had almost the same inhibition activities (6 ± 1 mm mean inhibition zones) on B. cereus, E. coli and E. faecalis. The n-hexane extract generally gave lower antibacterial activities than those of the other solvents for seeds and back. The results of the study showed that M. oleifera and M. ovalifolia had a degree of antibacterial properties against the selected test organisms that cause water borne diseases.
作者
Dorothea H. P. Shailemo
Habauka M. Kwaambwa
Martha Kandawa-Schulz
Titus A. M. Msagati
Dorothea H. P. Shailemo;Habauka M. Kwaambwa;Martha Kandawa-Schulz;Titus A. M. Msagati(Department of Chemistry and Biochemistry, University of Namibia, Windhoek, Namibia;Faculty of Health and Applied Sciences, Namibia University of Science and Technology, Windhoek, Namibia;College of Science Engineering and Technology, University of South Africa, The Science Campus, Johannesburg, South Africa)