Synthesis and Antimicrobial Activity of a New Class of Sulfone Linked Bisheterocycles

Synthesis and Antimicrobial Activity of a New Class of Sulfone Linked Bisheterocycles

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摘要 A new and novel class of bis(heterocycles) viz., bis pyrroles, pyrrolyl pyrazoles and pyrrolyl isoxazoles are prepared from 1-aroyl-2-styrylsulfonylethenes by 1,3-dipolar cycloaddition of tosylmethyl isocyanide, diazomethane, nitrile imines and nitrile oxides. The lead compounds are screened for antimicrobial activity. A new and novel class of bis(heterocycles) viz., bis pyrroles, pyrrolyl pyrazoles and pyrrolyl isoxazoles are prepared from 1-aroyl-2-styrylsulfonylethenes by 1,3-dipolar cycloaddition of tosylmethyl isocyanide, diazomethane, nitrile imines and nitrile oxides. The lead compounds are screened for antimicrobial activity.

作者 Venkatapuram Padmavathi Thunga Radha Lakshmi Bhumireddy Chinnachennaiahgari Venkatesh Konda Mahesh

机构地区不详

出处《International Journal of Organic Chemistry》 2011年第3期78-86,共9页 有机化学国际期刊（英文）

关键词 1-Aroyl-2-Styrylsulfonylethene 1 3-Dipolar CYCLOADDITION CHLORAMINE-T ANTIMICROBIAL Activity 1-Aroyl-2-Styrylsulfonylethene 1 3-Dipolar Cycloaddition Chloramine-T Antimicrobial Activity

分类号 O6 [理学—化学]

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International Journal of Organic Chemistry

2011年第3期

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Synthesis and Antimicrobial Activity of a New Class of Sulfone Linked Bisheterocycles

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