Stereoselective Synthesis of <i>cis</i>-Substituted-3’-anilino-2’, 3’-dihydro-4-2’-benzo[<i>b</i>]furanylcoumarins via Intramolecular Aldol Reactions
Stereoselective Synthesis of <i>cis</i>-Substituted-3’-anilino-2’, 3’-dihydro-4-2’-benzo[<i>b</i>]furanylcoumarins via Intramolecular Aldol Reactions
摘要
The present study reports the reaction of 4-bromomethylcoumarins with salicylidineaniline in acetone with two equivalents of potassium carbonate resulted in the formation of title compounds at room temperature via intramolecular aldolization. The obtained compound is thermodynamically and kinetically stable with highly stereoselective and excellent yield.
The present study reports the reaction of 4-bromomethylcoumarins with salicylidineaniline in acetone with two equivalents of potassium carbonate resulted in the formation of title compounds at room temperature via intramolecular aldolization. The obtained compound is thermodynamically and kinetically stable with highly stereoselective and excellent yield.
-
1Heli Kylmala,Antti Neuvonen,Reija Jokela.Enantioselective Aldol Reactions of Aliphatic Aldehydes with Singh’s Catalyst[J].International Journal of Organic Chemistry,2013,3(2):162-167. 被引量：1
-
2Mathieu Wagner,Yohan Contie,Clotilde Ferroud,Gilbert Revial.Enantioselective Aldol Reactions and Michael Additions Using Proline Derivatives as Organocatalysts[J].International Journal of Organic Chemistry,2014,4(1):55-67.
-
3Claus Vogel,Jochen Meier-Haack.Catalytic Cs<sub>2</sub>CO<sub>3</sub>Promotes “Silyl Method”-Type Polycondensation[J].Open Journal of Polymer Chemistry,2012,2(1):1-5.
