摘要
One pot criss-cross cycloaddition reaction of substituted 2,3-diaz-1,3-butadienes (<strong>1</strong>) and/or (<strong>2</strong>) with two equivalents of 2,3-dichloro-1,4-naphthoquinone in presence of dry benzene afforded bisnaphth[2,3-c]pyrazolidinetetrone derivatives (<strong>3</strong>) & (<strong>4</strong>). The chemical structure was achieved by elemental and spectral analysis. Biological activity of the synthesized compounds was tested against some micro-organisms, and has shown an interesting fungicidal activity and strongly to remarkable bactericidal activity.
One pot criss-cross cycloaddition reaction of substituted 2,3-diaz-1,3-butadienes (<strong>1</strong>) and/or (<strong>2</strong>) with two equivalents of 2,3-dichloro-1,4-naphthoquinone in presence of dry benzene afforded bisnaphth[2,3-c]pyrazolidinetetrone derivatives (<strong>3</strong>) & (<strong>4</strong>). The chemical structure was achieved by elemental and spectral analysis. Biological activity of the synthesized compounds was tested against some micro-organisms, and has shown an interesting fungicidal activity and strongly to remarkable bactericidal activity.
作者
Eman F. Kirolos
Amal S. Yanni
Eman F. Kirolos;Amal S. Yanni(College of Pharmacy, University of Florida, USA;Chemistry Department, Faculty of Science, Assiut University, Assiut, Egypt)
