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Successful treatment of a female pediatric patient with carbamazepine-induced toxic epidermal necrolysis: Active wound care and systemic therapy

Successful treatment of a female pediatric patient with carbamazepine-induced toxic epidermal necrolysis: Active wound care and systemic therapy
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摘要 We describe a 6-year-old female patient who developed carbamazepine-associated toxic epidermal necrolysis.With active wound care,systemic methylprednisolone and intravenous immunoglobulin pulse therapies and multidisciplinary supportive care,the patient improved significantly.This case indicates that improving the management of Stevens-Johnson syndrome/Toxic epidermal necrolysis patients requires attention not only to the process of wound management but also to individual supportive care and active therapeutic intervention.Only through this can standardized care,including muco-cutaneous and visceral wound care,be delivered to provide high-quality care with improved clinical prognosis and quality of life. We describe a 6-year-old female patient who developed carbamazepine-associated toxic epidermal necrolysis.With active wound care,systemic methylprednisolone and intravenous immunoglobulin pulse therapies and multidisciplinary supportive care,the patient improved significantly.This case indicates that improving the management of Stevens-Johnson syndrome/Toxic epidermal necrolysis patients requires attention not only to the process of wound management but also to individual supportive care and active therapeutic intervention.Only through this can standardized care,including muco-cutaneous and visceral wound care,be delivered to provide high-quality care with improved clinical prognosis and quality of life.
出处 《Pediatric Investigation》 2018年第2期114-118,共5页 儿科学研究(英文)
基金 National Natural Science Foundation of China(Grant no.81602754)%Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding(code:ZYLX201601)%Project of Excellent Talents in Beijing City(code:2013A003034000013)
关键词 Drug reaction WOUND CARE TOXIC EPIDERMAL necrolysis Drug reaction Wound care Toxic epidermal necrolysis
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