鼻病毒与儿童呼吸道感染的关系研究进展

Relationship between rhinovirus and pediatric respiratory infection

近年来儿童呼吸道感染的发生率和病死率在全世界范围内均有升高,其中鼻病毒与儿童呼吸道感染的关系尤为密切.除上呼吸道感染外,在感染期间下呼吸道也存在鼻病毒RNA.呼吸道上皮细胞是鼻病毒感染的靶细胞.近年有关鼻病毒感染与呼吸道感染关系的研究,为临床的治疗提供依据.鼻病毒引发呼吸道感染的病理机制还有待深入探讨.

In recent years,the incidence and mortality rate of pediatric respiratory infection have been increasing globally,with rhinovirus being of particular correlation to pediatric respiratory infection.In addition to upper respiratory tract infection,rhinovirus RNA is also found in the lower respiratory tract during the infection period.The epithelial cells of the upper respiratory tract are the target cells of rhinovirus.In recent years,studies done on the relationship between rhinovirus infection and upper respiratory tract infection have provided evidence for clinical treatment.Further investigation is needed on the pathological mechanisms of rhinovirus-induced respiratory infections.