Pathogenic genes of nevus sebaceous and its associated diseases

Introduction Nevus sebaceous (NS), also known as nevus sebaceous of Jadassohn, is a congenital sebaceous hyperplasia or organoid nevus. This benign congenital hamartoma is composed of abnormal epidermal and dermal com-ponents. The hamartomatous lesions, usually clinically present at birth, are most frequently distributed on areas with sebaceous glands, especially the scalp and face(1)NS originates from pluripotent primordial epithelial germ tissue and occurs in approximately 0.1%of newborns.