吉兰-巴雷综合征临床数据管理与分析系统的设计与实现

Design and implementation of Guillain-Barré syndrome clinical date management and analysis system

目的 根据吉兰-巴雷综合征(GBS)诊断与临床研究需要,开发一种科学规范、功能齐全、使用方便的GBS临床信息化管理系统,进行临床数据的管理及挖掘,为GBS临床研究提供平台.方法 确定GBS的临床数据项目,采用Visual Basic 6.0和Vista DB软件开发环境,基于嵌入式数据库开发可供单机使用的GBS临床数据管理与分析系统及数据库.结果 建立了包含近560项临床指标的GBS数据库,通过系统内置的数据挖掘和分析功能,可实现临床数据的可视化录入、组合搜索、统计分析、数据交换和文献更新等功能.西京医院已利用该系统录入并研究了274例GBS患者的临床及预后资料,结果证明该系统达到了设计目标.结论 基于信息技术,结合GBS相关的临床流行病学及神经病学专业知识,建立了标准的GBS的临床数据管理与分析系统及数据库,为GBS信息存储、更新、流行病学调查及预后研究提供基础.

Objective To design a scientific, standardized, fully functional, easy-to-use Guillain-Barré syndrome (GBS) clinical informatization management system, with the purpose to meet the needs of diagnosis and clinical research in patients with GBS. This system can manage and excavate clinical data and provide a platform for clinical research of GBS. Methods The clinical data items of GBS were identified. The Visual Basic 6.0 and Vista DB software development environment was used to develop the system and the related database based on embedded database. Results A GBS database including 560 clinical indicators were set up. Through the built-in data mining and analysis functions, the system can realize the functions of visualized data input, combination search, statistical analysis, data exchange and literature update. This system has been used in Xijing Hospital, and a total 274 clinical and prognostic records were recorded from the patients with GBS. The practical results proved that the system can achieve the design goals. Conclusions Based on the information technology and GBS-related clinical epidemiology and neurology expertise, a standard GBS clinical data management and analysis system and related database were established, which could provide a basis for GBS information storage, update, epidemiological investigation and prognosis.